A1852

Adenosine 5′-triphosphate (ATP) disodium salt hydrate

vial of 30 mg

• Synonym(s): ATP disodium hydrate
• Linear Formula: C₁₀H₁₄N₅O₁₃P₃Na₂ · xH₂O
• CAS Number: 34369-07-8
• Molecular Weight: 551.14 (anhydrous basis)
• EC Number: 213-579-1
• MDL number: MFCD00150755
• UNSPSC Code: 41106305
• eCl@ss: 32160414
• PubChem Substance ID: 24890593
• NACRES: NA.51

Properties

• biological source: microbial (Corynebacterium sp.)
• assay: ≥99% (HPLC)
• form: powder
• packaging: vial of 30 mg
• solubility: water: 50 mg/mL, clear, colorless
• storage temp.: −20°C
• SMILES string: Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• InChI key: NTBQNWBHIXNPRU-MSQVLRTGSA-L

Description

General description

Adenosine 5γ-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is used in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger CAMP. ATP provides the metabolic energy to drive metabolic pumps.

Application

ATP serves as a coenzyme in a wide array of enzymatic reactions.Adenosine 5′-triphosphate (ATP) disodium salt hydrate is used for tissue preparation and maintenance.[1]

Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been used:

• in rat hippocampal slice cultures to mimic synaptic signalling[2]
• in the isolation of plasmid from primary porcine alveolar macrophages (PAMs)[3]
• as a component of hot reaction kinase buffer for in gel kinase assay[4]

Biochem/physiol Actions

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• ppe: Eyeshields, Gloves, type N95 (US)