A185
Ambenonium dichloride
solid
Synonym(s):
N,N′-[(1,2-Dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl)] bis[2-chloro-N,N-diethylbenzene-methanaminium]
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About This Item
Empirical Formula (Hill Notation):
C28H42Cl4N4O2
CAS Number:
Molecular Weight:
608.47
EC Number:
MDL number:
UNSPSC Code:
12352200
form
solid
color
white
solubility
H2O: soluble
SMILES string
[Cl-].[Cl-].CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)Cc1ccccc1Cl)Cc2ccccc2Cl
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A S Hodge et al.
Molecular pharmacology, 41(5), 937-942 (1992-05-01)
Steady state patterns of inhibition of purified human erythrocyte acetylcholinesterase by three inhibitors were analyzed. Edrophonium acted essentially as a competitive inhibitor, whereas tacrine and ambenonium gave mixed competitive and uncompetitive inhibition with acetylthiocholine as substrate. Inhibition constants for the
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