93394

Trizma^® Buffer substance

pH 9.0

• Synonym(s): Tris Buffer substance, Tris(hydroxymethyl)aminomethane Buffer substance
• MDL number: MFCD00012590
• UNSPSC Code: 12161700
• PubChem Substance ID: 57653554

Properties

• form: powder or crystals
• mol wt: average mol wt 124.6
• pH: 8.7±0.1 (37 °C, 0.05 M); 9.0±0.1 (25 °C, 0.05 M); 9.6±0.1 (5 °C, 0.05 M)
• solubility: H₂O: 0.67 g/mL, clear, colorless
• SMILES string: Cl.NC(CO)(CO)CO
• InChI: 1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H
• InChI key: QKNYBSVHEMOAJP-UHFFFAOYSA-N

Description

General description

Trizma^® and its salts are used as biological buffers to control the pH of body fluids in vitro and in vivo. It acts as a precursor for polymers, oxazolones (with carboxylic acids), and oxazolidines (with aldehydes). Trizma can serve as an alkalizing agent in treating acidosis of the blood.

Application

Trizma^® Buffer substance has been used as an eluent in asymmetrical flow field-flow fractionation (AFFFF).

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves