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90916

Sigma-Aldrich

ZnAF-2F

≥95.0% (HPCE)

Synonym(s):

6-{2-[Bis(2-pyridylmethyl)amino]ethylamino}-2′,7′-difluorofluorescein

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About This Item

Empirical Formula (Hill Notation):
C34H26F2N4O5
CAS Number:
443302-09-8
Molecular Weight:
608.59
MDL number:
MFCD08277019
UNSPSC Code:
12352101
PubChem Substance ID:
57653416
NACRES:
NC.07

assay

≥95.0% (HPCE)

form

powder

fluorescence

λex 492 nm; λem 517 nm in PBS, Zn2+

storage temp.

−20°C

SMILES string

OC(=O)c1ccc(NCCN(Cc2ccccn2)Cc3ccccn3)cc1C4=C5C=C(F)C(=O)C=C5Oc6cc(O)c(F)cc46

InChI

1S/C34H26F2N4O5/c35-27-14-25-31(16-29(27)41)45-32-17-30(42)28(36)15-26(32)33(25)24-13-20(7-8-23(24)34(43)44)39-11-12-40(18-21-5-1-3-9-37-21)19-22-6-2-4-10-38-22/h1-10,13-17,39,41H,11-12,18-19H2,(H,43,44)

InChI key

HPADXJLXFKDPBV-UHFFFAOYSA-N

Application

suitable for the fluorimetric detection of Zn2+

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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Tahereh Ziglari et al.
Inhalation toxicology, 32(2), 86-95 (2020-03-29)
Background: While the role of lysosomal membrane permeabilization (LMP) in NP-induced inflammatory responses has been recognized, the underlying mechanism of LMP is still unclear. The assumption has been that zinc oxide (ZnO)-induced LMP is due to Zn2+; however, little is
Tomoya Hirano et al.
Journal of the American Chemical Society, 124(23), 6555-6562 (2002-06-06)
The development and cellular applications of novel fluorescent probes for Zn2+, ZnAF-1F, and ZnAF-2F are described. Fluorescein is used as a fluorophore of ZnAFs, because its excitation and emission wavelengths are in the visible range, which minimizes cell damage and

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