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48130

Sigma-Aldrich

Kinetin

≥99.0% (HPLC)

Synonym(s):

6-Furfurylaminopurine, N6-Furfuryladenine

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About This Item

Empirical Formula (Hill Notation):
C10H9N5O
CAS Number:
525-79-1
Molecular Weight:
215.21
Beilstein/REAXYS Number:
21703
EC Number:
208-382-2
MDL number:
MFCD00075757
UNSPSC Code:
51111800
PubChem Substance ID:
57651147
NACRES:
NA.77

Quality Level

100

assay

≥99.0% (HPLC)

ign. residue

≤0.05%

mp

264-270 °C (dec.) (lit.)
269-271 °C (dec.)

SMILES string

C(Nc1ncnc2[nH]cnc12)c3ccco3

InChI

1S/C10H9N5O/c1-2-7(16-3-1)4-11-9-8-10(13-5-12-8)15-6-14-9/h1-3,5-6H,4H2,(H2,11,12,13,14,15)

InChI key

QANMHLXAZMSUEX-UHFFFAOYSA-N

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Application


  • Phenolic profiling and bioactivity assessment of in vitro propagated Psidium cattleianum Sabine: This study highlights the use of kinetin in enhancing phenolic compound production in tissue cultures, demonstrating its potential in plant biotechnology and pharmaceutical applications (El-Deeb et al., 2024).

  • The impact of chemical and hormonal treatments to improve seed germination and seedling growth of Juniperus procera Hochst. ex Endi.: Research shows kinetin′s effectiveness in improving seed germination rates and seedling vigor, underlining its role as a valuable plant growth regulator (Jabbour and Alzahrani, 2024).

  • Callus Induction Followed by Regeneration and Hairy Root Induction in Common Buckwheat: Kinetin was used to successfully induce callus and facilitate regeneration in buckwheat, providing insights into its applications in genetic engineering and crop improvement (Omelchenko et al., 2024).

  • Long-term organogenic callus cultivation of Ranunculus illyricus L.: This study utilizes kinetin in the long-term cultivation of callus tissues, contributing to the conservation of plant species and enhancing our understanding of plant developmental biology (Kocot et al., 2024).

  • Optimizing medicinal hemp production with synergistic light-enhanced technologies and organic biorefinery approaches: Incorporating kinetin in light-enhanced growth protocols for hemp showcases its utility in optimizing plant production systems, potentially increasing yield and quality (Puttharak et al., 2024).


Biochem/physiol Actions

Kinetin has been studied as a treatment for many human disease states caused by pre-mRNA splicing errors, including familial dysautonomia and neurofibromatosis.

Other Notes

Plant growth regulator

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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H. Mohr et al.
Lehrbuch der Pflanzenphysiologie, 370-370 (1978)
C.O. Miller
Annu. Rev. Phytochem. Soc. Eur., 12, 395-395 (1961)
Eva Pros et al.
European journal of human genetics : EJHG, 18(5), 614-617 (2009-11-26)
Neurofibromatosis type 1 is one of the most common neurocutaneous autosomal dominant disorders. It is caused by mutations in the neurofibromatosis type 1 (NF1) gene and approximately 30-40% of them affect the correct splicing of NF1 pre-mRNA. In this report
Sergey Shabala et al.
Plant, cell & environment, 32(2), 194-207 (2008-11-22)
Nutrient acquisition in the mature root zone is under systemic control by the shoot and the root tip. In maize, exposure of the shoot to light induces short-term (within 1-2 min) effects on net K+ and H+ transport at the
Matthew M Hims et al.
Journal of molecular medicine (Berlin, Germany), 85(2), 149-161 (2007-01-09)
Mutations that affect the splicing of pre-mRNA are a major cause of human disease. Familial dysautonomia (FD) is a recessive neurodegenerative disease caused by a T to C transition at base pair 6 of IKBKAP intron 20. This mutation results
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