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42455

Sigma-Aldrich

3,3′-Dioctylthiacarbocyanine iodide

BioReagent, suitable for fluorescence, ≥98.0% (HPCE)

Synonym(s):

DiSC8(3)

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About This Item

Empirical Formula (Hill Notation):
C33H45IN2S2
CAS Number:
Molecular Weight:
660.76
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

product line

BioReagent

assay

≥98.0% (HPCE)

solubility

DMSO: soluble
methanol: soluble

fluorescence

λex 510 nm; λem 587 nm in phosphate buffer/SDS pH 7.0

suitability

suitable for fluorescence

SMILES string

[I-].CCCCCCCCN1C(\Sc2ccccc12)=C\C=C\c3sc4ccccc4[n+]3CCCCCCCC

InChI

1S/C33H45N2S2.HI/c1-3-5-7-9-11-17-26-34-28-20-13-15-22-30(28)36-32(34)24-19-25-33-35(27-18-12-10-8-6-4-2)29-21-14-16-23-31(29)37-33;/h13-16,19-25H,3-12,17-18,26-27H2,1-2H3;1H/q+1;/p-1

InChI key

MYIUORMVYDSCRZ-UHFFFAOYSA-M

Application

3,3′-Dioctylthiacarbocyanine iodide [DiSC8(3)] is a cyanine dye that may be used similar to 3,3′-dipropylthiadicarbocyanine iodide [DiSC(3)(5)] for studies on membrane potential.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Jaromír Plášek et al.
Journal of bioenergetics and biomembranes, 44(5), 559-569 (2012-07-20)
The fluorescent dye 3,3'-dipropylthiadicarbocyanine, diS-C(3)(3), is a suitable probe to monitor real changes of plasma membrane potential in yeast cells which are too small for direct membrane potential measurements with microelectrodes. A method presented in this paper makes it possible
R J W Brooijmans et al.
Journal of bacteriology, 189(14), 5203-5209 (2007-05-15)
Lactococcus lactis, a facultative anaerobic lactic acid bacterium, is known to have an increased growth yield when grown aerobically in the presence of heme. We have now established the presence of a functional, proton motive force-generating electron transfer chain (ETC)
Jaeyong Cho et al.
Biochimica et biophysica acta, 1828(3), 1153-1158 (2012-12-25)
Dioscin is a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica. We investigated the antifungal effect of dioscin against different fungal strains and its antifungal mechanism(s) in Candida albicans cells. Using the propidium iodide

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