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Key Documents

COO/COA

39490

MEGA-8 500 mM solution

Name: MEGA-8 500 mM solution
Brand: SIGMA

Synonym(s):

MEGA-8 solution, Detergent Screening Solution 35/Kit-No 66317

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About This Item

CAS Number:

85316-98-9

MDL number:

MFCD00134152

UNSPSC Code:

12352200

PubChem Substance ID:

57649901

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description

non-ionic

CMC

application(s)

sample preservation

storage temp.

2-8°C

SMILES string

CCCCCCCC(=O)N(C)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C15H31NO6/c1-3-4-5-6-7-8-13(20)16(2)9-11(18)14(21)15(22)12(19)10-17/h11-12,14-15,17-19,21-22H,3-10H2,1-2H3/t11-,12+,14+,15+/m0/s1

InChI key

SBWGZAXBCCNRTM-CTHBEMJXSA-N

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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The structures of 1-deoxy-(N-methyloctanamido)-D-glucitol (MEGA-8) and 1-deoxy-(N-methylundecanamido)-D-glucitol (MEGA-11).

G A Jeffrey et al.

Acta crystallographica. Section B, Structural science, 45 ( Pt 4), 447-452 (1989-08-01)

1-Deoxy-(N-methyloctanamido)-D-glucitol, C15H31NO6 (MEGA-8), crystallizes in space group P2(1)2(1)2(1), Mr = 321.4, a = 4.865 (1), b = 9.186 (3), c = 39.097 (9) A, V = 1747.24 A3, Z = 4, Dx = 1.22 Mg m-3, lambda (Cu K alpha)

Differential solubilization of lipids along with membrane proteins by different classes of detergents.

P Banerjee et al.

Chemistry and physics of lipids, 77(1), 65-78 (1995-08-01)

Membrane proteins are typically extracted by detergent concentrations of 0.5-2.0%, using detergent/protein ratios of 1:1 to 3:1. We have compared the ability of 14 different detergents from seven different structural and ionic classes, at a concentration of 2.0% and a

Solubility properties of the alkylmethylglucamide surfactants.

A Walter et al.

Biochimica et biophysica acta, 1029(1), 67-74 (1990-11-02)

The critical micelle concentration (CMC) and the ability to solubilize and form vesicles from phospholipids are important criteria for the selection of a surfactant for reconstitution protocols. The CMC and its temperature dependence were determined for an homologous series of

Detergents stabilize the conformation of phosphodiesterase 6.

Bo Y Baker et al.

Biochemistry, 50(44), 9520-9531 (2011-10-08)

Membrane-bound phosphodiesterase 6 (PDE6) plays an important role in visual signal transduction by regulating cGMP levels in rod photoreceptor cells. Our understanding of PDE6 catalysis and structure suffers from inadequate characterization of the α and β subunit catalytic core, interactions

Purification and photoaffinity labeling of the I-Ak histocompatibility molecule.

I F Luescher et al.

Journal of immunological methods, 135(1-2), 233-245 (1990-12-31)

Photoaffinity labeling was used to evaluate optimal conditions for purification of I-A k histocompatibility molecules in functionally active form. We assessed the biological activity of I-A k primarily by its binding of the hen egg-white lysozyme (HEL) peptide from residues

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