Tobramycin microparticulate powders containing the hydrophobic adjunct sodium stearate were studied for their use as pulmonary formulations in dry powder inhalers. Spray-dried powders were characterized in terms of particle size distribution, morphology, crystallinity, drug dissolution rate, toxicity on epithelial lung
Solvent-induced crystal morphology transformation in a ternary soap system: sodium stearate crystalline fibers and platelets.
Liang J, et al.
Langmuir, 17(21), 6447-6454 (2001)
A Phase Rule Study of the System Sodium Stearate-Water.
McBain JW, et al.
The Journal of Physical Chemistry, 44(9), 1013-1024 (1940)
Sodium stearate-catalyzed multicomponent reactions for efficient synthesis of spirooxindoles in aqueous micellar media.
Molecular and cellular biochemistry, 331(1-2), 31-40 (2009-05-16)
Chronic exposure to elevated free fatty acids, in particular long chain saturated fatty acids, provokes endoplasmic reticulum (ER) stress and cell death in a number of cell types. The perturbations to the ER that instigate ER stress and activation of
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