20808

Cholesterol

meets analytical specification of NF

• Synonym(s): 3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol
• Empirical Formula (Hill Notation): C₂₇H₄₆O
• CAS Number: 57-88-5
• Molecular Weight: 386.65
• Beilstein/REAXYS Number: 1915888
• EC Number: 200-353-2
• MDL number: MFCD00003646
• UNSPSC Code: 12352200
• eCl@ss: 39023139
• PubChem Substance ID: 24852491

Properties

• optical activity: [α]20/D −38 to −34°, c = 2% in dioxane
• quality: meets analytical specification of NF
• ign. residue: ≤0.1% (as SO₄)
• loss: ≤0.3% loss on drying, 60 °C, 4 h (vacuum)
• bp: 360 °C (lit.)
• mp: 147-149 °C (lit.); 147-150 °C
• solubility: H₂O: insoluble; acetone: soluble; alcohol: slightly soluble; alcohol: very soluble; benzene: soluble; chloroform: soluble at 1 gm in 4.5 ml; diethyl ether: soluble at 1 gm in 2.8 ml; dioxane: soluble; ethyl acetate: soluble; hexane: soluble; oil: soluble; petroleum ether: soluble; pyridine: soluble at 1 gm in 1.5 ml
• density: 1.067 g/mL at 25 °C (lit.)
• SMILES string: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• InChI key: HVYWMOMLDIMFJA-DPAQBDIFSA-N
• Gene Information: human ... POLA1(5422) , TOP2A(7153) ; rat ... Ar(24208) , Polb(29240)

Description

Biochem/physiol Actions

Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)