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18472

Sigma-Aldrich

Betaine solution

0.1 M

Synonym(s):

Additive Screening Solution 40/Kit-No 78374

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About This Item

Linear Formula:
(CH3)3N+CH2COO−
CAS Number:
107-43-7
Molecular Weight:
117.15
Beilstein/REAXYS Number:
3537113
MDL number:
MFCD00012123
UNSPSC Code:
12352200
PubChem Substance ID:
57647743

concentration

0.1 M

density

1.00 g/mL at 20 °C

storage temp.

2-8°C

SMILES string

C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3

InChI key

KWIUHFFTVRNATP-UHFFFAOYSA-N

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
1062459

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Bernd C Schwahn et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(3), 512-514 (2003-01-29)
Hyperhomocysteinemia, a proposed risk factor for cardiovascular disease, is also observed in other common disorders. The most frequent genetic cause of hyperhomocysteinemia is a mutated methylenetetrahydrofolate reductase (MTHFR), predominantly when folate status is impaired. MTHFR synthesizes a major methyl donor
Pål I Holm et al.
Clinical chemistry, 49(2), 286-294 (2003-02-01)
The quaternary ammonium compounds, choline and betaine, and dimethylglycine (DMG) reside along a metabolic pathway linked to the synthesis of neurotransmitters and membrane phospholipids and to homocysteine remethylation and, therefore, folate status. Lack of a convenient, high-throughput method for the
Per Magne Ueland
Journal of inherited metabolic disease, 34(1), 3-15 (2010-05-07)
Choline is an essential nutrient, but is also formed by de novo synthesis. Choline and its derivatives serve as components of structural lipoproteins, blood and membrane lipids, and as a precursor of the neurotransmitter acetylcholine. Pre-and postnatal choline availability is
Per Magne Ueland et al.
Clinical chemistry and laboratory medicine, 43(10), 1069-1075 (2005-10-04)
Betaine serves as a methyl donor in a reaction converting homocysteine to methionine, catalysed by the enzyme betaine-homocysteine methyltransferase. It has been used for years to lower the concentration of plasma total homocysteine (tHcy) in patients with homocystinuria, and has
M R Olthof et al.
Current drug metabolism, 6(1), 15-22 (2005-02-22)
High plasma concentrations of homocysteine may increase risk of cardiovascular disease. Folic acid lowers plasma homocysteine by 25% maximally, because 5-methyltetrahydrofolate is a methyl donor in the remethylation of homocysteine to methionine. Betaine (trimethylglycine) is also a methyl donor in
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