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18360

Sigma-Aldrich

Bromosulfalein

for liver diagnosis, for microscopy (Hist.)

Synonym(s):

Phenoltetrabromophthalein-3′,3″-disulfonic acid disodium salt, Sulfobromophthalein disodium salt

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About This Item

Empirical Formula (Hill Notation):
C20H8Br4Na2O10S2
CAS Number:
Molecular Weight:
838.00
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:

grade

for liver diagnosis
for microscopy (Hist.)

SMILES string

[Na+].[Na+].OC(=O)c1c(Br)c(Br)c(Br)c(Br)c1\C(c2ccc(O)c(c2)S([O-])(=O)=O)=C3/C=CC(=O)C(=C3)S([O-])(=O)=O

InChI

1S/C20H10Br4O10S2.2Na/c21-16-14(15(20(27)28)17(22)19(24)18(16)23)13(7-1-3-9(25)11(5-7)35(29,30)31)8-2-4-10(26)12(6-8)36(32,33)34;;/h1-6,25H,(H,27,28)(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2/b13-8+;;

InChI key

HXUITPQMHVLBNV-LIYVDSPJSA-L

Application

Reagent for the quantitative determination of proteins.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


Certificates of Analysis (COA)

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Mirko Leonhardt et al.
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Contrast-enhancing magnetic resonance imaging with the liver-specific agent gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) has been shown to improve the detection rate of focal lesions. There is evidence from preclinical studies that multidrug organic anion transporters are involved in hepatic uptake of
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The therapeutic effects and metabolism of mesalazine (5-aminosalicylic acid) in patients with inflammatory bowel disease require intracellular accumulation of the drug in intestinal epithelial cells and hepatocytes. The molecular mechanisms of mesalazine uptake into cells have not been characterized so
Chen Yanxiao et al.
Life sciences, 89(1-2), 1-6 (2011-04-07)
The purpose of the present study was to investigate the roles of transporters in the renal excretion of entecavir. We analyzed the effect of probenecid, cimetidine, sulfobromophthalein sodium (BSP), verapamil, inhibitors of organic anion transporter (OAT), organic cation transporter (OCT)
Wen Zhang et al.
European journal of drug metabolism and pharmacokinetics, 42(4), 669-676 (2016-11-07)
Ophiopogonin D (OPD) is one of the main active ingredients of SMI (Shenmai injection) which is widely used in clinical practice in China. Our previous study indicated  that OPD might be transported from blood into liver mediated by organic anion
Cecilia L Balaban et al.
Artificial organs, 35(5), 508-515 (2011-05-21)
The insults sustained by transplanted livers (hepatectomy, hypothermic preservation, and normothermic reperfusion) could compromise hepatic function. Hydrogen sulfide (H₂S) is a physiologic gaseous signaling molecule, like nitric oxide (NO) and carbon monoxide (CO). We examined the effect of diallyl disulfide

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