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Key Documents

T8258

Sigma-Aldrich

Trifluoroacetic anhydride

liquid

Synonym(s):

TFAA

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About This Item

Linear Formula:
(CF3CO)2O
CAS Number:
Molecular Weight:
210.03
Beilstein/REAXYS Number:
746197
EC Number:
MDL number:
UNSPSC Code:
12352100

vapor pressure

6.28 psi ( 20 °C)

form

liquid

color

clear colorless

refractive index

n20/D 1.3 (lit.)

bp

39.5-40 °C (lit.)

mp

−65 °C (lit.)

density

1.511 g/mL at 20 °C (lit.)

SMILES string

FC(F)(F)C(=O)OC(=O)C(F)(F)F

InChI

1S/C4F6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10

InChI key

QAEDZJGFFMLHHQ-UHFFFAOYSA-N

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pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

supp_hazards

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 2

ppe

Faceshields, Gloves, Goggles


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Angelos Halaris et al.
Journal of psychiatric research, 66-67, 118-126 (2015-05-27)
A pro-inflammatory state and a dysregulation in the tryptophan/kynurenine pathway have been documented in depression. This study examined whether treatment with the SSRI, escitalopram (ESC), could suppress inflammation and favorably shift metabolites of the kynurenine pathway in patients with major
Hidenori Kinoshita et al.
Journal of the American Chemical Society, 132(18), 6412-6418 (2010-04-17)
Reaction screening of nucleophilic reaction partners for addition to N-diphenylphosphinylimines employing lanthanum(III) triflate as a catalyst and trifluoroacetic anhydride (TFAA) as an activator is reported. A number of tandem processes leading to novel chemotypes including aza-Prins/intramolecular Friedel-Crafts annulations have been
Philippe Nuhant et al.
The Journal of organic chemistry, 74(24), 9413-9421 (2009-11-21)
Aminopentadienals resulting from the condensation of tryptamine or homoveratrylamine with glutaconaldehydes were treated with trifluoroacetic anhydride, allowing the formation of tetrahydro-beta-carbolines and tetrahydroisoquinolines bearing an enal function. In this N-acyl Pictet-Spengler reaction the electrophilicity of the aminopentadienals was dramatically increased
L Giannetti et al.
Analytica chimica acta, 700(1-2), 11-15 (2011-07-12)
Avermectines are antiparasitic agents widely used as veterinary drugs for food producing animals. The European Community, due to their side effects, limited the use of these molecules establishing maximum residue limits (MRLs) in some foods. A validated qualitative and quantitative
Sooyeun Lee et al.
Forensic science international, 178(2-3), 207-212 (2008-05-27)
Quality assurance is one of the major issues in forensic analytical laboratories, where the need for a reference material (RM) has rapidly increased. RMs are very useful for method development and validation, internal quality control or proficiency tests. In the

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