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Key Documents

33717

Sigma-Aldrich

Thiourea

puriss. p.a., reag. Ph. Eur., ≥99%

Synonym(s):

Sulfourea, Thiocarbamide

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About This Item

Linear Formula:
NH2CSNH2
CAS Number:
Molecular Weight:
76.12
Beilstein/REAXYS Number:
605327
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

agency

reag. Ph. Eur.

grade

puriss. p.a.

assay

≥99%

ign. residue

≤0.1% (as SO4)

loss

≤0.5% loss on drying

mp

170-176 °C (lit.)

SMILES string

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

Gene Information

mouse ... Ephx2(13850)

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Application

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Elaine M Boyle et al.
The Journal of organic chemistry, 78(17), 8312-8319 (2013-08-01)
Thiourea-functionalized Tröger's base receptors 1 and 2 have been synthesized and evaluated as novel for the recognition of anions. Receptor 2 gave rise to significant changes in the absorption spectrum upon titration with AcO(-) and H2PO4(-) and acted as a
Mathieu P Lalonde et al.
Journal of the American Chemical Society, 135(5), 1891-1894 (2013-01-17)
A highly enantio- and diastereoselective synthesis of indolo- and benzoquinolizidine compounds has been developed through the formal aza-Diels-Alder reaction of enones with cyclic imines. This transformation is catalyzed by a new bifunctional primary aminothiourea that achieves simultaneous activation of both
Mireille Vonlanthen et al.
The Journal of organic chemistry, 78(8), 3980-3988 (2013-03-09)
Proof that sulfur is a viable reporting element for the development of fluorescent chemosensors for metal ions is presented. To date, the majority of metal-responsive fluorescent chemosensors have relied on metal-nitrogen coordination to provide a fluorescence response, most commonly by
Shrinivas Venkataraman et al.
Macromolecular rapid communications, 34(8), 652-658 (2013-03-14)
Readily water-soluble PEGylated amphiphiles containing bis-thiourea-based molecular recognition units at the interface of hydrophobic and hydrophilic blocks are developed. Self-assembly of these amphiphiles is found to be dependent on the exact chemical composition of the hydrophobic component. Elongated, spherical, and
David Weisbrod et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(18), E1685-E1694 (2013-04-17)
Proper expression and function of the cardiac pacemaker is a critical feature of heart physiology. Two main mechanisms have been proposed: (i) the "voltage-clock," where the hyperpolarization-activated funny current If causes diastolic depolarization that triggers action potential cycling; and (ii)

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