33709

Tetrahydrofuran

≥99.9% (GC), contains ~250 mg/L 2, 6-di-tert.-butyl-4-methylphenol as stabilizer, puriss. p.a.

• Synonym(s): THF, Butylene oxide, Oxolane, Tetramethylene oxide
• Empirical Formula (Hill Notation): C₄H₈O
• CAS Number: 109-99-9
• Molecular Weight: 72.11
• Beilstein/REAXYS Number: 102391
• EC Number: 203-726-8
• MDL number: MFCD00005356
• UNSPSC Code: 12352005
• PubChem Substance ID: 57648904
• assay: ≥99.9% (GC)
• bp: 65-67 °C (lit.)
• vapor pressure: 114 mmHg ( 15 °C); 143 mmHg ( 20 °C)

Properties

• Product Name: Tetrahydrofuran, puriss. p.a., ≥99.9% (GC)
• vapor density: 2.5 (vs air)
• vapor pressure: 114 mmHg ( 15 °C); 143 mmHg ( 20 °C)
• grade: puriss. p.a.
• assay: ≥99.9% (GC)
• form: liquid
• autoignition temp.: 610 °F
• contains: ~250 mg/L 2,6-di-tert.-butyl-4-methylphenol as stabilizer
• expl. lim.: 1.8-11.8 %
• impurities: ≤0.001% free acid (as CH₃COOH); ≤0.001% non-volatile matter; ≤0.005% peroxides (as H₂O₂); ≤0.05% water (Karl Fischer)
• color: APHA: <20
• refractive index: n20/D 1.407 (lit.)
• bp: 65-67 °C (lit.)
• mp: −108 °C (lit.)
• solubility: H₂O: soluble
• density: 0.889 g/mL at 25 °C (lit.)
• cation traces: Al: ≤0.5 mg/kg; B: ≤0.02 mg/kg; Ba: ≤0.1 mg/kg; Ca: ≤0.5 mg/kg; Cd: ≤0.05 mg/kg; Co: ≤0.02 mg/kg; Cr: ≤0.02 mg/kg; Cu: ≤0.02 mg/kg; Fe: ≤0.1 mg/kg; Mg: ≤0.1 mg/kg; Mn: ≤0.02 mg/kg; Ni: ≤0.02 mg/kg; Pb: ≤0.1 mg/kg; Sn: ≤0.1 mg/kg; Zn: ≤0.1 mg/kg
• SMILES string: C1CCOC1
• InChI: 1S/C4H8O/c1-2-4-5-3-1/h1-4H2
• InChI key: WYURNTSHIVDZCO-UHFFFAOYSA-N

Description

General description

Tetrahydrofuran (THF) is widely employed as a solvent. It constitutes the key fragment of various natural products (polyether antibiotics).[1] THF forms a double hydrate with hydrogen sulfide. The crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies.[2]

Application

Tetrahydrofuran has been used for the dissolution of poly-ε-caprolactone (PCL), during the preparation of poly-ε-caprolactone (PCL)-hydroxyapatite (HA) scaffolds.[3] It has been used for the dissolution of 1,3-diaminopentane, during the synthesis of acrylate-terminated poly(5-amino-1-pentanol-co-1,4-butanediol diacrylate) (C32)-1,3-diaminopentane (117) polymer.[4]

Packaging

bottled under inert gas

Other Notes

Go to our Greener Alternative-2-Methyl Tetrahydrofuran

Go to our Greener Alternative-Cyclopentyl methylether

A -D suffix exists for administrative purposes only.
All -D packages are 100% the same product, same quality, same specification as the package sizes previously sold without a -D.

Safety Information

• pictograms: GHS02,GHS08,GHS07
• signalword: Danger
• hcodes: H225,H302,H319,H335,H336,H351
• pcodes: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system, Respiratory system
• supp_hazards: EUH019
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: -6.2 °F - closed cup
• flash_point_c: -21.2 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter