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135011

Sigma-Aldrich

1,2-Dihydroxybenzene

ReagentPlus®, ≥99%

Synonym(s):

Pyrocatechol, 1,2-Benzenediol, 1,2-Dihydroxybenzene, 2-Hydroxyphenol, Catechol

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$27.82
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$41.60
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$72.30
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$272.00
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$303.66

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5 G
$27.82
100 G
$41.60
500 G
$72.30
3 KG
$272.00
5 KG
$303.66

About This Item

Linear Formula:
C6H4-1,2-(OH)2
CAS Number:
120-80-9
Molecular Weight:
110.11
Beilstein/REAXYS Number:
471401
EC Number:
204-427-5
MDL number:
MFCD00002188
UNSPSC Code:
12352100
PubChem Substance ID:
24848193
NACRES:
NA.21

$27.82

List Price$34.90Save 20%

In StockDetails

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vapor density

3.8 (vs air)

Quality Level

200

vapor pressure

1 mmHg ( 75 °C)
10 mmHg ( 118.3 °C)

product line

ReagentPlus®

assay

≥99%

form

solid

bp

245 °C (lit.)

mp

100-103 °C (lit.)

SMILES string

Oc1ccccc1O

InChI

1S/C6H6O2/c7-5-3-1-2-4-6(5)8/h1-4,7-8H

InChI key

YCIMNLLNPGFGHC-UHFFFAOYSA-N

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General description

1,2-Dihydroxybenzene (a phenolic compound)[1] is a useful industrial chemical.[2] It is an ortho isomeric form of dihydroxybenzene.[3] It is commonly referred to as catechol or pyrocatechol. Its standard molar enthalpy of combustion and sublimation at 298.15K have been evaluated by static-bomb calorimetry and microcalorimetry, respectively.[4]

Application

1,2-Dihydroxybenzene may be used as raw material for the industrial synthesis of rubber, dyes, plastics, pharmaceuticals and cosmetics.[3]
1,2-Dihydroxybenzene in combination with amberlite XAD-2, can be used as a chelating resin in the determination of metal ions, using atomic absorption spectrophotometry (AAS).[5]

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

260.6 °F - closed cup

flash_point_c

127 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW5183
MKCV0899
MKCT4053
MKCV1554
MKCS2724

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Synthesis, characterization and applications of pyrocatechol modified amberlite XAD-2 resin for preconcentration and determination of metal ions in water samples by flame atomic absorption spectrometry (FAAS)
Tewari KP and Singh KA
Talanta, 53(4), 823- 833 (2001)
Catechol suppresses EGF-induced cell transformation by inhibiting ERK2 activity as confirmed by a crystallographic study.
Malakhova M, et al.
Cancer Research, 73(8), 2234-2234 (2013)
Andrew A Horwitz et al.
Cell systems, 1(1), 88-96 (2016-05-03)
CRISPR-Cas genome engineering in yeast has relied on preparation of complex expression plasmids for multiplexed gene knockouts and point mutations. Here we show that co-transformation of a single linearized plasmid with multiple PCR-generated guide RNA (gRNA) and donor DNA cassettes
Thiago C Canevari et al.
The Analyst, 138(1), 315-324 (2012-11-17)
This paper describes the development, characterization and application of an Nb(2)O(5) film formed on the surface of a carbon ceramic material, SiO(2)/C, obtained by a sol-gel method, using the spin-coating technique. The working electrode using this material will be designated
Enthalpies of combustion of 1, 2-dihydroxybenzene and of six alkylsubstituted 1, 2-dihydroxybenzenes.
Da Silva MDMCR, et al.
The Journal of Chemical Thermodynamics, 16(12), 1149-1155 (1984)
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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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