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116114

Sigma-Aldrich

Trichloroacetic acid

reagent grade, 98%

Synonym(s):

TCA

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About This Item

Linear Formula:
Cl3CCOOH
CAS Number:
76-03-9
Molecular Weight:
163.39
Beilstein/REAXYS Number:
970119
EC Number:
200-927-2
MDL number:
MFCD00004177
UNSPSC Code:
12352100
PubChem Substance ID:
329749496

grade

reagent grade

vapor density

<1 (vs air)

vapor pressure

1 mmHg ( 51 °C)
1 mmHg ( 51 °C)

assay

98%

refractive index

n20/D 1.62 (lit.)

bp

196 °C (lit.)

mp

54-58 °C (lit.)

solubility

water: soluble 81.7 g/L at 20 °C

density

1.62 g/mL at 25 °C (lit.)

SMILES string

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

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Application

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

replaced by

Product No.
Description
Pricing

pictograms

CorrosionEnvironment
GHS05,GHS09

signalword

Danger

hcodes

H314,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk_germany

WGK 2

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
MKBB8282
S45465
01823MH
09612MH
09712MH

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A method for the determination of desoxyribonucleic acid, ribonucleic acid, and phosphoproteins in animal tissues.
G SCHMIDT et al.
The Journal of biological chemistry, 161, 83-89 (1945-01-01)
Solubility of albumin in alcohol after precipitation by trichloroacetic acid: a simplified procedure for separation of albumin.
J R DEBRO et al.
Nature, 178(4541), 1067-1067 (1956-11-10)
A microcolorimetric method for the determination of inorganic phosphorus.
H H TAUSSKY et al.
The Journal of biological chemistry, 202(2), 675-685 (1953-06-01)
S L Herren-Freund et al.
Toxicology and applied pharmacology, 90(2), 183-189 (1987-09-15)
Trichloroethylene (TCE) has previously been shown to be carcinogenic in mouse liver when administered by daily gavage in corn oil. The metabolism of TCE results, in part, in the formation of trichloroacetic acid (TCA) as a major metabolite and dichloroacetic
V Arjunan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 97, 625-638 (2012-08-04)
The structural investigations of the molecular complex of 2-methyl-4-nitroaniline with trichloroacetic acid, namely 2-methyl-4-nitroanilinium trichloroacetate trichloroacetic acid (C(11)H(10)Cl(6)N(2)O(6)) have been performed by means of single crystal and powder X-ray diffraction method. The complex was formed with accompanying proton transfer from
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