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10400

Sigma-Aldrich

Aniline

puriss. p.a., ACS reagent, ≥99.5% (GC)

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About This Item

Linear Formula:
C6H5NH2
CAS Number:
62-53-3
Molecular Weight:
93.13
Beilstein/REAXYS Number:
605631
EC Number:
200-539-3
MDL number:
MFCD00007629
UNSPSC Code:
12352100
PubChem Substance ID:
24846633

grade

ACS reagent
puriss. p.a.

vapor density

3.22 (185 °C, vs air)

vapor pressure

0.7 mmHg ( 25 °C)

assay

≥99.5% (GC)

autoignition temp.

1139 °F

expl. lim.

11 %

impurities

hydrocarbons, in accordance
≤0.003% nitrobenzene (C6H5NO2)
≤0.1% water

ign. residue

≤0.005%

refractive index

n20/D 1.586 (lit.)
n20/D 1.586

bp

184 °C (lit.)

mp

−6 °C (lit.)

density

1.022 g/mL at 25 °C (lit.)

cation traces

Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Zn: ≤1 mg/kg

SMILES string

Nc1ccccc1

InChI

1S/C6H7N/c7-6-4-2-1-3-5-6/h1-5H,7H2

InChI key

PAYRUJLWNCNPSJ-UHFFFAOYSA-N

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Biochem/physiol Actions

The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.

Physical properties

Material darkens in storage to reddish-brown with no loss in purity.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1

target_organs

Blood

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

158.0 °F - closed cup

flash_point_c

70 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
BCBF0294V
BCBD8586V
BCBB3013V
BCBC8487V
BCBC8487

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