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11140949001

Roche

UTP

=98% (HPLC), solution, (1 mM UTP = 9.9 A260 units), pkg of 400 μL (40 μmol; 100mM)

Synonym(s):

UTP, lithium salt

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About This Item

UNSPSC Code:
41105600

description

Lithium salt

assay

98% (HPLC)

form

solution

packaging

pkg of 400 μL (40 μmol; 100mM)

manufacturer/tradename

Roche

shipped in

dry ice

storage temp.

−20°C

General description

UTP is a 100 mM solution of the lithium salt (pH 7).
Contents:
UTP, lithium salt, 100 mM

Application

UTP, lithium salt, is suitable for applications such as in vitro RNA transcription.[1]

Biochem/physiol Actions

UTP lithium salt acts as a biased agonist in activation of P2γ receptor, a G-protein coupled receptor (GPCR) and results in the elevation of cytosolic calcium levels.[2]

Quality

Typical analysis:
  • ≥98% UTP (HPLC), ≤1.5% UDP (HPLC), ≤0.5% UMP (HPLC).
  • Tested for the absence of RNases according to the current Quality Control procedures.

Unit Definition

1 mM UTP = 9.9 A260 units

Other Notes

For life science research only. Not for use in diagnostic procedures.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

does not flash

flash_point_c

does not flash


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Cell Biology Assays: Essential Methods (2009)
UTP is not a biased agonist at human P2Y 11 receptors.
Morrow G B, et al.
Purinergic Signaling, 10(4), 581-585 (2014)
Oxidized low-density lipoprotein is a novel predictor of interferon responsiveness in chronic hepatitis C infection
Solbach, P, et al.
Cellular and molecular gastroenterology and hepatology, 1.3, 285-294 (2015)
Riku Nagai et al.
Methods and protocols, 4(3) (2021-07-22)
The rates of translation elongation or termination in eukaryotes are modulated through cooperative molecular interactions involving mRNA, the ribosome, aminoacyl- and nascent polypeptidyl-tRNAs, and translation factors. To investigate the molecular mechanisms underlying these processes, we developed an in vitro translation

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