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M0505

Sigma-Aldrich

Methylamine hydrochloride

≥98%

Synonym(s):

Methanaminium chloride, Methylamine monohydrochloride, Methylammonium chloride, Monomethylammonium chloride

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About This Item

Linear Formula:
CH3NH2 · HCl
CAS Number:
593-51-1
Molecular Weight:
67.52
Beilstein/REAXYS Number:
3588822
EC Number:
209-795-0
MDL number:
MFCD00012849
UNSPSC Code:
12352100
PubChem Substance ID:
57654342
NACRES:
NA.22

assay

≥98%

form

powder or crystals

bp

225-230 °C/15 mmHg (lit.)

mp

231-233 °C (lit.)

solubility

H2O: 1 g in 10 mL, clear, colorless

SMILES string

Cl[H].CN

InChI

1S/CH5N.ClH/c1-2;/h2H2,1H3;1H

InChI key

NQMRYBIKMRVZLB-UHFFFAOYSA-N

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General description

Methylamine hydrochloride is used as a buildingblock for the synthesis of various organic compounds.

Application

Methylamine hydrochloride can be used as a reactant to synthesize:
  • Betahistine via aza-Michael reaction with 2-vinylpyridine in water.
  • Azatripyrrolic and azatetrapyrrolic macrocycles by reacting with pyrrole and formaldehyde via base-catalyzed Mannich reaction.
  • Tetrahydropyridines via Aza-Diels–Alder reaction with dienes and aldehydes.
  • N-methylsecondary arylamines from aryl chlorides via nickel-catalyzed amination reaction.

Related product

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Description
Pricing

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

408.7 °F - closed cup

flash_point_c

209.3 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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