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Key Documents

T90395

Sigma-Aldrich

DL-m-Tyrosine

99%

Synonym(s):

(±)-2-Amino-3-(3-hydroxyphenyl)propionic acid, 3-(3-Hydroxyphenyl)-DL-alanine

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About This Item

Linear Formula:
HOC6H4CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
181.19
Beilstein/REAXYS Number:
2416853
EC Number:
MDL number:
UNSPSC Code:
12352103

assay

99%

mp

280-285 °C (dec.) (lit.)

SMILES string

NC(Cc1cccc(O)c1)C(O)=O

InChI

1S/C9H11NO3/c10-8(9(12)13)5-6-2-1-3-7(11)4-6/h1-4,8,11H,5,10H2,(H,12,13)

InChI key

JZKXXXDKRQWDET-UHFFFAOYSA-N

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signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Raúl A Ruggiero et al.
Cancer research, 71(22), 7113-7124 (2011-11-16)
Concomitant tumor resistance (CR) is a phenomenon originally described in 1906 in which a tumor-bearing host is resistant to the growth of secondary tumor implants and metastasis. Although recent studies have indicated that T-cell-dependent processes mediate CR in hosts bearing
Wenjun Zhang et al.
Biochemistry, 50(24), 5401-5403 (2011-05-28)
Phenylalanine hydroxylase (PheH) is an iron(II)-dependent enzyme that catalyzes the hydroxylation of aromatic amino acid l-phenylalanine (L-Phe) to l-tyrosine (L-Tyr). The enzymatic modification has been demonstrated to be highly regiospecific, forming proteinogenic para-Tyr (p-Tyr) exclusively. Here we biochemically characterized the
Philip H Elsinga et al.
Current medicinal chemistry, 13(18), 2139-2153 (2006-08-22)
The dopaminergic system plays a major role in neurological and psychiatric disorders such as Parkinson's disease, Huntington's disease, tardive dyskinea and schizophrenia. Knowledge on altered dopamine synthesis, receptor densities and status are important for understanding the mechanisms underlying the pathogenesis
Tengfang Huang et al.
Phytochemistry, 75, 60-66 (2011-12-24)
m-Tyrosine is a non-protein amino acid that is structurally similar to the common protein amino acids p-tyrosine and phenylalanine. Copious amounts of m-tyrosine can be found in root exudates of the fine fescue cultivar, Festuca rubra L. ssp. commutata (Chewings
Chiu-Lan Chen et al.
Journal of toxicology and environmental health. Part A, 65(3-4), 327-336 (2002-03-26)
Chewing areca quid (AQ) has been implicated as a major risk factor for the development of oral squamous-cell carcinoma (OSCC). Recent studies have suggested that AQ-generated reactive oxygen species (ROS) is one of the contributing factors for oral carcinogenesis. However

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