T36404
o-Toluic acid
99%
Synonym(s):
2-Methylbenzoic acid
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All Photos(3)
About This Item
Linear Formula:
CH3C6H4CO2H
CAS Number:
Molecular Weight:
136.15
Beilstein/REAXYS Number:
1072103
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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assay
99%
bp
258-259 °C (lit.)
mp
102-104 °C (lit.)
density
1.062 g/mL at 25 °C (lit.)
SMILES string
Cc1ccccc1C(O)=O
InChI
1S/C8H8O2/c1-6-4-2-3-5-7(6)8(9)10/h2-5H,1H3,(H,9,10)
InChI key
ZWLPBLYKEWSWPD-UHFFFAOYSA-N
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General description
o-Toluic acid is an aromatic carboxylic acid and an organic intermediate used in pesticides and medicines.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
298.4 °F - closed cup
flash_point_c
148 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
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The iron(II)- and 2-oxoglutarate (2OG)-dependent dioxygenase AlkB from Escherichia coli (EcAlkB) repairs alkylation damage in DNA by direct reversal. EcAlkB substrates include methylated bases, such as 1-methyladenine (m(1)A) and 3-methylcytosine (m(3)C), as well as certain bulkier lesions, for example the
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The Escherichia coli AlkB protein (EcAlkB) is a DNA repair enzyme which reverses methylation damage such as 1-methyladenine (1-meA) and 3-methylcytosine (3-meC). The mammalian AlkB homologues ALKBH2 and ALKBH3 display EcAlkB-like repair activity in vitro, but their substrate specificities are
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ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic activity of alkylating agents, chemicals significantly contributing to tumor formation and used in cancer therapy.
Adsorption of 2-methylbenzoic acid onto MCM-41 mesoporous material: kinetics and equilibrium studies
Daniela A et al.
Journal of Sol-Gel Science and Technology, 64, 1-8 (2012)
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