S6525
Sulfanilamide
99%
Synonym(s):
p-Aminobenzenesulfonamide
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About This Item
Linear Formula:
H2NC6H4SO2NH2
CAS Number:
Molecular Weight:
172.20
Beilstein/REAXYS Number:
511852
EC Number:
MDL number:
UNSPSC Code:
12352103
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assay
99%
mp
164-166 °C (lit.)
SMILES string
Nc1ccc(cc1)S(N)(=O)=O
InChI
1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
InChI key
FDDDEECHVMSUSB-UHFFFAOYSA-N
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Product No.
Description
Pricing
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Hasan Turkmen et al.
Bioorganic & medicinal chemistry letters, 15(2), 367-372 (2004-12-18)
A series of sulfonamides has been obtained by reacting sulfanilamide or 5-amino-1,3,4-thiadiazole-2-sulfonamide with omega-chloroalkanoyl chlorides, followed by replacement of the omega-chlorine atom with secondary amines. Tails incorporating heterocyclic amines belonging to the morpholine, piperidine and piperazine ring systems have been
Francesco Mincione et al.
Bioorganic & medicinal chemistry letters, 15(17), 3821-3827 (2005-07-26)
A new series of thioureido-substituted sulfonamides were prepared by reacting 4-isothiocyanato- or 4-isothiocyanatoethyl-benzenesulfonamide with amines, hydrazines, or amino acids bearing moieties that can lead to an enhanced hydrosolubility, such as 2-dimethylamino-ethylamine, fluorine-containing aromatic amines/hydrazines, an aminodiol, heterocyclic polyamines (derivatives of
Vijay K Agrawal et al.
Bioorganic & medicinal chemistry letters, 16(7), 2044-2051 (2006-02-07)
A quantitative Structure-activity relationship study (QSAR) on a set of carbonic anhydrase (CA, EC 4.2.1.1) inhibitors is reported using first-order valence connectivity index ((1)chi(v)). The inhibitory activity against three isozymes CAI, CAII (cystolic forms), and CAIV (membrane bound form), some
Isao Nishimori et al.
Bioorganic & medicinal chemistry letters, 15(17), 3828-3833 (2005-07-26)
The inhibition of the last human carbonic anhydrase (CA, EC 4.2.1.1) isozyme (hCA XIV) discovered has been investigated with a series of sulfonamides, including some clinically used derivatives (acetazolamide, methazolamide, ethoxzolamide, dichlorophenamide, dorzolamide, brinzolamide, benzolamide, and zonisamide), as well as
Luca Puccetti et al.
Bioorganic & medicinal chemistry letters, 15(9), 2359-2364 (2005-04-20)
The tumor-associated transmembrane carbonic anhydrase (CA, EC 4.2.1.1) isozyme IX (CA IX) is overexpressed in hypoxic tumors and appears to be involved in acidification of the tumor microenvironment, a process correlated with cancer progression and bad prognosis. The acidification may
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