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P7207

Sigma-Aldrich

1,5-Pentamethylenetetrazole

98%

Synonym(s):

Pentylenetetrazole, α,β-Cyclopentamethylenetetrazole, 1,5-Pentamethylenetetrazole, 6,7,8,9-Tetrahydro-5H-tetrazolo[1,5-a]azepine, Metrazole

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About This Item

Empirical Formula (Hill Notation):
C6H10N4
CAS Number:
Molecular Weight:
138.17
EC Number:
MDL number:
UNSPSC Code:
12352103

assay

98%

bp

194 °C/12 mmHg (lit.)

mp

59-61 °C (lit.)

SMILES string

C1CCc2nnnn2CC1

InChI

1S/C6H10N4/c1-2-4-6-7-8-9-10(6)5-3-1/h1-5H2

InChI key

CWRVKFFCRWGWCS-UHFFFAOYSA-N

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Description
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pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Idan Elbaz et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(4), 1220-1234 (2014-12-04)
Neuronal-activity-regulated pentraxin (NARP/NPTX2/NP2) is a secreted synaptic protein that regulates the trafficking of glutamate receptors and mediates learning, memory, and drug addiction. The role of NPTX2 in regulating structural synaptic plasticity and behavior in a developing vertebrate is indefinite. We
Jenifer A Bradley et al.
Toxicological sciences : an official journal of the Society of Toxicology, 163(1), 240-253 (2018-02-13)
Drug-induced seizure liabilities produce significant compound attrition during drug discovery. Currently available in vitro cytotoxicity assays cannot predict all toxicity mechanisms due to the failure of these assays to predict sublethal target-specific electrophysiological liabilities. Identification of seizurogenic and other electrophysiological

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