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P50919

Sigma-Aldrich

Propargylamine hydrochloride

95%

Synonym(s):

2-Propynylamine hydrochloride, 3-Amino-1-propyne hydrochloride

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About This Item

Linear Formula:
HC≡CCH2NH2 · HCl
CAS Number:
15430-52-1
Molecular Weight:
91.54
Beilstein/REAXYS Number:
3669858
EC Number:
239-440-5
MDL number:
MFCD00012907
UNSPSC Code:
12352100
PubChem Substance ID:
24898593
NACRES:
NA.22

Quality Level

100

assay

95%

form

powder

reaction suitability

reaction type: click chemistry

mp

179-182 °C (lit.)

storage temp.

2-8°C

SMILES string

Cl.NCC#C

InChI

1S/C3H5N.ClH/c1-2-3-4;/h1H,3-4H2;1H

InChI key

IKXNIQJDNKPPCH-UHFFFAOYSA-N

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pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
SHBR5341
BCCL1156
SHBQ6223
SHBQ5675
STBF1364V

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Thomas Hermanns et al.
Life science alliance, 3(9) (2020-07-29)
Deubiquitinating enzymes (DUBs) are important regulators of the posttranslational protein ubiquitination system. Mammalian genomes encode about 100 different DUBs, which can be grouped into seven different classes. Members of other DUB classes are found in pathogenic bacteria, which use them
Anna Fodor et al.
Organic & biomolecular chemistry, 8(20), 4575-4581 (2010-08-27)
A new, heterogeneous, 4 A molecular sieve-supported copper(ii) catalyst was developed and was used successfully in the A(3) coupling of alkynes, aldehydes and amines under simple reaction conditions.
Claudio Gnaccarini et al.
Organic & biomolecular chemistry, 10(27), 5258-5265 (2012-06-02)
Transglutaminases (TGases) catalyse the transamidation of glutamine residues with primary amines. Herein we report the first FRET-based activity assay for the direct detection of the ligation (transamidation) reaction mediated by tissue TGase (TG2). This novel assay was then used in
Adrian Sulistio et al.
Chemical communications (Cambridge, England), 47(4), 1151-1153 (2010-12-15)
Highly functionalized water soluble core cross-linked star (CCS) polymers having degradable cores and hierarchical functionalities spanning from the peripheral groups along the arms to the core have been synthesized entirely from amino acid building blocks. The core-isolated moieties were shown
Orit Bar-Am et al.
Journal of Alzheimer's disease : JAD, 21(2), 361-371 (2010-06-18)
The anti-Parkinsonian, irreversible, selective monoamine oxidase (MAO)-B inhibitors, selegiline (deprenyl, (R)-N-methyl-N-(1-phenylpropan-2-yl) prop-2-yn-1-amine) and rasagiline (Azilect, N-propargyl-1(R)-aminoindan), have been proven to possess neuroprotective/neurorestorative activities in cell cultures and animal models of neurodegenerative diseases. Structure-activity studies provide evidence that neuroprotection is associated
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