M3701

2-Mercaptoethanol

98%

• Synonym(s): β-Mercaptoethanol, 2-Hydroxyethylmercaptan, BME, Thioethylene glycol
• Linear Formula: HSCH₂CH₂OH
• CAS Number: 60-24-2
• Molecular Weight: 78.13
• Beilstein/REAXYS Number: 773648
• EC Number: 200-464-6
• MDL number: MFCD00004890
• UNSPSC Code: 12352103

Properties

• vapor density: 2.69 (vs air)
• vapor pressure: 1 mmHg ( 20 °C)
• assay: 98%
• expl. lim.: 18 %
• concentration: 14.3 M (pure liquid)
• refractive index: n20/D 1.500 (lit.)
• bp: 157 °C (lit.)
• density: 1.114 g/mL at 25 °C (lit.)
• SMILES string: OCCS
• InChI: 1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
• InChI key: DGVVWUTYPXICAM-UHFFFAOYSA-N

Description

Application

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

Charge transfer agent for the preparation of polyvinyl chloride.[1] Synthon for the preparation of 1,3-oxathiolanes.[2][3]

Other Notes

This product has been replaced by M6250-ALDRICH | 2-Mercaptoethanol ≥99.0%

Safety Information

• pictograms: GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H301 + H331,H310,H315,H317,H318,H361d,H373,H410
• pcodes: P273 - P280 - P301 + P310 - P302 + P352 + P310 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral
• target_organs: Liver,Heart
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 165.2 °F - closed cup
• flash_point_c: 74 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter