M2501

5-Methoxyindole-2-carboxylic acid ethyl ester

crystalline

• Synonym(s): 2-Carbethoxy-5-methoxyindole, 2-Ethoxycarbonyl-5-methoxyindole, Ethyl 5-methoxyindole-2-carboxylate, NSC 30929
• Empirical Formula (Hill Notation): C₁₂H₁₃NO₃
• CAS Number: 4792-58-9
• Molecular Weight: 219.24
• MDL number: MFCD00047163
• UNSPSC Code: 12352100
• PubChem Substance ID: 57654363
• NACRES: NA.22

Properties

• form: crystalline
• color: yellow to orange
• storage temp.: −20°C
• SMILES string: CCOC(=O)c1cc2cc(OC)ccc2[nH]1
• InChI: 1S/C12H13NO3/c1-3-16-12(14)11-7-8-6-9(15-2)4-5-10(8)13-11/h4-7,13H,3H2,1-2H3
• InChI key: NPIUAXNFAUGNHP-UHFFFAOYSA-N

Description

Application

Reactant for preparation of:

• Ligands with binding specificity towards the GABA receptor
• Sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes
• Anticancer agents
• Integrase strand-transfer inhibitors (INSTIs)
• Inhibitor of Proliferation of Colon Cancer Cells
• Isomeridianin G as GSK-3? inhibitors
• HIV-1 integrase inhibitors
• Inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable