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Key Documents

I6806

Sigma-Aldrich

Iodoacetic acid

98%

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About This Item

Linear Formula:
ICH2CO2H
CAS Number:
Molecular Weight:
185.95
Beilstein/REAXYS Number:
1739079
EC Number:
MDL number:
UNSPSC Code:
12352200

assay

98%

mp

77-79 °C (lit.)

SMILES string

OC(=O)CI

InChI

1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5)

InChI key

JDNTWHVOXJZDSN-UHFFFAOYSA-N

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Application

Enolic radical[1] and ketene[2] precursor. SH modifier.[3]
Reagent for the modification of cysteine residues in proteins.

replaced by

Product No.
Description
Pricing

pictograms

Skull and crossbonesCorrosion

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1A

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Tetrahedron, 49, 8465-8465 (1993)
Tetrahedron, 50, 7579-7579 (1994)
R Nemani et al.
Archives of biochemistry and biophysics, 300(1), 24-29 (1993-01-01)
Chemical modification of the sulfhydryl residues of the catalytic subunits of protein phosphatases 1 and 2A was studied. Both enzymes were inactivated by a variety of thiol group reagents. Mercurial compounds were the most effective inactivators. Of the alkylating agents
X D Wang et al.
Journal of dental research, 92(10), 918-924 (2013-08-13)
Temporomandibular joint osteoarthritis (TMJOA) is clinically characterized by female preponderance, with a female-to-male ratio of more than 2:1; however, the underlying mechanism remains obscure. We examined the effects of estrogen on TMJOA induced by monosodium iodoacetate. Female rats were randomly
Catherine E Ferland et al.
Phytotherapy research : PTR, 26(9), 1278-1285 (2012-09-28)
The aim of the present study was to evaluate whether eugenol, the main constituent of clove oil, has the capacity to provide analgesia in the monoiodoacetate-induced rat model of osteoarthritis. Animals (n = 6/group) received either eugenol (20 or 40 mg/kg) or a

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