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Key Documents

88544

Sigma-Aldrich

Thio-L-citrulline

≥98.0%

Synonym(s):

(S)-2-Amino-5-(thioureido)pentanoic acid, N5-Aminothioxomethyl-L-ornithine

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About This Item

Empirical Formula (Hill Notation):
C6H13N3O2S
CAS Number:
Molecular Weight:
191.25
Beilstein/REAXYS Number:
6844478
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.22

assay

≥98.0%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

N[C@@H](CCCNC(N)=S)C(O)=O

InChI

1S/C6H13N3O2S/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1

InChI key

BKGWACHYAMTLAF-BYPYZUCNSA-N

Gene Information

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Biochem/physiol Actions

Potent and selective inhibitor of neuronal and endothelial isoforms of nitric oxide synthase.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Yu Na Wu et al.
Pflugers Archiv : European journal of physiology, 472(12), 1743-1755 (2020-09-18)
Nitric oxide (NO) affects mitochondrial activity through its interactions with complexes. Here, we investigated regulations of complex I (C-I) and complex II (C-II) by neuronal NO synthase (nNOS) in the presence of fatty acid supplementation and the impact on left

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