Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

86728

Sigma-Aldrich

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrayl-tetrakis(methylphosphonic acid)

≥97.0% (CHN)

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C12H32N4O12P4
CAS Number:
Molecular Weight:
548.30
Beilstein/REAXYS Number:
3579556
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

assay

≥97.0% (CHN)

SMILES string

OP(O)(=O)CN1CCN(CCN(CCN(CC1)CP(O)(O)=O)CP(O)(O)=O)CP(O)(O)=O

Other Notes

Complexing agent. Lanthanide complexes are used as NMR shift reagents; Complexation properties with earth-alkali ions

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hazel B Breitz et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 47(3), 534-542 (2006-03-04)
166Ho-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethylene-phosphonate (DOTMP) is a tetraphosphonate molecule radiolabeled with 166Ho that localizes to bone surfaces. This study evaluated pharmacokinetics and radiation-absorbed dose to all organs from this beta-emitting radiopharmaceutical. After two 1.1-GBq administrations of 166Ho-DOTMP, data from whole-body counting using a
Jaime Simón et al.
Nuclear medicine and biology, 39(6), 770-776 (2012-03-31)
The therapeutic potential of the bone-seeking radiopharmaceutical 153Sm-labeled 1,4,7,10-tetraazacyclododecanetetramethylenephosphonic acid (153Sm-DOTMP) was assessed by measuring its dosage-dependent skeletal uptake at two chelant-to-metal ratios and its source organ residence times at a chelant-to-metal ratio of 1.5:1. A similar agent, 153Sm-labeled ethylenediaminetetramethylenephosphonic
Anupama Datta et al.
Cancer biotherapy & radiopharmaceuticals, 24(1), 123-128 (2009-02-27)
The convenient synthetic methodology and in vivo stability of the bone-seeking gamma-radiation-emitting compound, (99m)Tc-DOTMP are described in this paper. The radiolabeling efficiency was found to be >97%, and the stability in serum indicated that (99m)Tc remained bound to the chelate
J P Van Duynhoven et al.
European journal of biochemistry, 216(2), 507-517 (1993-09-01)
Scrutiny of NOE data available for the protein encoded by gene V of the filamentous phage IKe (IKe GVP), resulted in the elucidation of a beta-sheet structure which is partly five stranded. The DNA-binding domain of IKe GVP was investigated
D.W. Swinkels et al.
Rec. Trav. Chim., 110, 124-124 (1991)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service