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Key Documents

862088

Sigma-Aldrich

Lysergol

97%

Synonym(s):

9,10-Didehydro-6-methylergoline-8β-methanol

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About This Item

Empirical Formula (Hill Notation):
C16H18N2O
CAS Number:
Molecular Weight:
254.33
EC Number:
MDL number:
UNSPSC Code:
12352200

assay

97%

SMILES string

CN1C[C@H](CO)C=C2[C@H]1Cc3c[nH]c4cccc2c34

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pictograms

Skull and crossbones

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Danger

Hazard Classifications

Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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E M Parker et al.
Journal of neurochemistry, 67(5), 2096-2103 (1996-11-01)
5-Hydroxytryptamine elicits its physiological effects by interacting with a diverse group of receptors. Two of these receptors, the 5-HT1D beta and the 5-HT1E receptors, are approximately 60% identical in the transmembrane domains that presumably form the ligand binding site yet
Shinsuke Inuki et al.
Organic letters, 10(22), 5239-5242 (2008-10-30)
Ergot alkaloids and their synthetic analogs have been reported to exhibit broad biological activity. We investigated direct construction of the C/D ring system of ergot alkaloids based on palladium-catalyzed domino cyclization of amino allenes. With this biscyclization as the key
Shinsuke Inuki et al.
The Journal of organic chemistry, 76(7), 2072-2083 (2011-03-03)
Enantioselective total synthesis of the biologically important indole alkaloids (+)-lysergol, (+)-isolysergol, and (+)-lysergic acid is described. Key features of these total synthesis include (1) a facile synthesis of a chiral 1,3-amino alcohol via the Pd(0)- and In(I)-mediated reductive coupling reaction
D Groó et al.
Polish journal of pharmacology and pharmacy, 40(6), 593-601 (1988-11-01)
Different ergot structures (lumilysergol and lysergol) were chlorinated or brominated in the position 2, and the development of antidopaminergic activity was studied. The tested 2-halo-lysergols exerted neuroleptic-like action indicated by the suppression of conditioned avoidance response (CAR), and other effects
V Kren et al.
Bioorganic & medicinal chemistry, 4(6), 869-876 (1996-06-01)
New glycosides derived from ergot alkaloids elymoclavine and DH-lysergol were synthesized by chemoenzymatic methods. beta-Glucosides were obtained either by chemical method or by transglycosylation (glycosidase from Aspergillus oryzae), lactosides were prepared by further extension of carbohydrate chain using beta-1,4-galactosyltransferase (bovine

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