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860859

Sigma-Aldrich

Citrinin

98%

Synonym(s):

4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C13H14O5
CAS Number:
518-75-2
Molecular Weight:
250.25
Beilstein/REAXYS Number:
5282243
EC Number:
208-257-2
MDL number:
MFCD00006912
UNSPSC Code:
12352103
PubChem Substance ID:
329769436

Quality Level

100

assay

98%

SMILES string

C[C@H]1OC=C2C(O)=C(C(O)=O)C(=O)C(C)=C2[C@@H]1C

InChI

1S/C13H14O5/c1-5-7(3)18-4-8-9(5)6(2)11(14)10(12(8)15)13(16)17/h4-5,7,15H,1-3H3,(H,16,17)/t5-,7-/m1/s1

InChI key

CQIUKKVOEOPUDV-IYSWYEEDSA-N

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
17209EY
05978EQ
11802PN
08863AN
05643BY

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Shuqiang Liu et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(6), 856-861 (2012-05-09)
A previous study has shown that CTN (Citrinin) inhibits mouse testosterone production. In this study, the mechanism by which testosterone production is inhibited by CTN in rat Leydig cells was investigated, and the morphological evidence of apoptosis, including nuclei fragmentation
Yishan Yang et al.
Fungal biology, 116(2), 225-233 (2012-02-01)
FlbA (fluffy low brlA expression), a regulator of the G protein signalling (RGS) pathway, has been implicated in the control of hyphal development, sporulation, mycotoxin/pigment production in many kinds of filamentous fungi and yeasts. In the current study, a FlbA-like
Mohammad Rafiqul Islam et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3537-3547 (2012-07-10)
The mycotoxin citrinin can cause mycotoxic nephropathy, cytotoxicity and genotoxicity. To investigate the immune modulatory effects, CTN was orally administered to female BALB/c mice at the dose of 1, 5, or 10 mg/kg body weight for 14 days, and several
Hassan Hajjaj et al.
Journal of food science, 77(3), M156-M159 (2012-03-06)
Amino acids were used as sole nitrogen sources to examine their effects on the production of water-soluble red pigments and citrinin by Monascus ruber ATCC 96218 cultivated on chemically defined media. In general, when glycine, tyrosine, arginine, serine, or histidine
H K Frank
Zeitschrift fur Ernahrungswissenschaft, 31(3), 164-177 (1992-09-01)
Citrinin, a nephrotoxic mycotoxin, has been of growing importance also for the "International Agency for Research on Cancer", ever since its presumable role in the occurrence of Balcan endemic nephropathy (BEN) was discussed at the congress on "Mycotoxins, Endemic Nepthropathy
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