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857831

Sigma-Aldrich

Cytochalasin E from Aspergillus clavatus

Synonym(s):

Cytochalasin E from Aspergillus clavatus

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About This Item

Empirical Formula (Hill Notation):
C28H33NO7
CAS Number:
Molecular Weight:
495.56
Beilstein/REAXYS Number:
1096975
EC Number:
MDL number:
UNSPSC Code:
12352103

SMILES string

C[C@H]1C\C=C\[C@H]2[C@@H]3O[C@]3(C)[C@@H](C)[C@H]4[C@H](Cc5ccccc5)NC(=O)[C@@]24OC(=O)O\C=C\[C@@](C)(O)C1=O

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Repr. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Lin Xiao et al.
World journal of microbiology & biotechnology, 29(1), 11-17 (2012-08-23)
A moderately halophilic fungus F1 was isolated from a marine solar saltern in Weihai, China. The identification of the fungus F1 was performed by the morphological characteristics, physiological and biochemical tests as well as phylogenetic analysis based on ITS (internal
Cíntia Silva dos Santos et al.
Microbiology and immunology, 54(1), 1-10 (2010-01-09)
As interactions between bacteria and macrophages dictate the outcome of most infectious diseases, analyses of molecular mechanisms of non-opsonic phagocytosis should lead to new approaches for the prevention of diphtheria and systemic Corynebacterium diphtheriae infections. The present study aimed to
Kangjian Qiao et al.
Metabolic engineering, 13(6), 723-732 (2011-10-11)
Cytochalasins are a group of fungal secondary metabolites with diverse structures and bioactivities, including cytochalasin E produced by Aspergillus clavatus, which is a potent anti-angiogenic agent. Here, we report the identification and characterization of the cytochalasin gene cluster from A.
F Willermain et al.
The British journal of ophthalmology, 86(12), 1417-1421 (2002-11-26)
To investigate the capability of retinal pigment epithelium (RPE) cells to phagocytose T lymphocytes and to further analyse the immunobiological consequences of this phagocytosis. Human RPE cells pretreated or not by cytochalasin, a phagocytosis inhibitor, were co-cultured with T lymphocytes
Qing-Yi Lu et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 11(4), 1675-1683 (2005-03-05)
Alteration of actin polymerization and loss of actin filaments is a marker of cellular dedifferentiation and early malignant transformation. To study this phenomenon, an in vitro human urothelial model consisting of two cell lines, HUC-PC and MC-T11, were incorporated into

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