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850624

Sigma-Aldrich

Hydantoin-5-acetic acid

98%

Synonym(s):

2,4-Dioxoimidazolidine-5-acetic acid, 5-Hydantoinacetic acid, DL-5-(Carboxymethyl)hydantoin

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About This Item

Empirical Formula (Hill Notation):
C5H6N2O4
CAS Number:
Molecular Weight:
158.11
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

98%

form

powder

mp

214-215 °C (dec.) (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)CC1NC(=O)NC1=O

InChI

1S/C5H6N2O4/c8-3(9)1-2-4(10)7-5(11)6-2/h2H,1H2,(H,8,9)(H2,6,7,10,11)

InChI key

DQQLZADYSWBCOX-UHFFFAOYSA-N

Application

Reactant for synthesis of:
  • Nonfolate compounds as antiparasitic agents inhibiting pteridine reductase
  • 2,4-Azolidinedione-acetic acid derivatives as anticancer agents
  • Anti-inflammatory and analgesic drugs
  • Amides via polystyrene-supported N-hydroxybenxotriazole resin

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Marta Chylińska et al.
Molecules (Basel, Switzerland), 25(16) (2020-08-23)
Current demand for new protective materials ensuring sterility is systematically growing. The purpose of this work was the synthesis of the biocidal N-halamine hydantoin-containing chitosan (CS-CMH-Cl) and characterization of its properties. The functionalization of the chitosan by 5-hydantoinacetic acid substitution

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