79229

N-Boc-1,6-hexanediamine

≥98.0% (NT)

• Synonym(s): N-Boc-1,6-diaminohexane, tert-Butyl-N-(6-aminohexyl)carbamate
• Empirical Formula (Hill Notation): C₁₁H₂₄N₂O₂
• CAS Number: 51857-17-1
• Molecular Weight: 216.32
• Beilstein/REAXYS Number: 2219107
• MDL number: MFCD00671489
• UNSPSC Code: 12352116
• PubChem Substance ID: 57652779
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: ≥98.0% (NT)
• form: liquid
• reaction suitability: reagent type: cross-linking reagent
• refractive index: n20/D 1.462
• density: 0.965 g/mL at 20 °C (lit.)
• functional group: Boc; amine
• SMILES string: NCCCCCCNC(OC(C)(C)C)=O
• InChI: 1S/C11H24N2O2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12/h4-9,12H2,1-3H3,(H,13,14)
• InChI key: RVZPDKXEHIRFPM-UHFFFAOYSA-N

Description

Application

N-Boc-1,6-hexanediamine can be used as a linear hexyl spacer (C₆-spacer) to synthesize:

• Biodegradable poly(disulfide amine)s for gene delivery.
• A multifunctional dendrimer for theranostics.
• Polyamide platinum anti-cancer complexes designed to target cancer specific DNA sequences.
• Self-assembled monolayers (SAMs) that resist adsorption of proteins.
• [N-(6-(4-Hydroxy-6-isopropylamino-1,3,5-triazin-2-ylamino)hexyl)-5-hydroxy-1,4-naphthoquinone-3-propionamide] (JUG-HATZ), which can be used in designing electrochemical immunosensors.

Reagent for the introduction of a C₆-spacer.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 257.0 °F - closed cup
• flash_point_c: 125 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter