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73489

Sigma-Aldrich

L-α-Neopentylglycine

≥98.0% (TLC)

Synonym(s):

γ-Methyl-L-leucine, (S)-2-Amino-4,4-dimethylpentanoic acid, L-γ-Methylleucine

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About This Item

Empirical Formula (Hill Notation):
C7H15NO2
CAS Number:
57224-50-7
Molecular Weight:
145.20
MDL number:
MFCD00066079
UNSPSC Code:
12352209
PubChem Substance ID:
57652480
NACRES:
NA.22

Quality Level

100

assay

≥98.0% (TLC)

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

application(s)

peptide synthesis

SMILES string

[H][C@](N)(CC(C)(C)C)C(O)=O

InChI

1S/C7H15NO2/c1-7(2,3)4-5(8)6(9)10/h5H,4,8H2,1-3H3,(H,9,10)/t5-/m0/s1

InChI key

LPBSHGLDBQBSPI-YFKPBYRVSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG7350
BCBR9192V
BCBJ9918V
BCBC1880V
BCBC1880

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J L Fauchère et al.
International journal of peptide and protein research, 18(3), 249-255 (1981-09-01)
The modified Strecker synthesis of Patel & Worsley was combined with an enzymatic deamidation in the final step, to produce the title compound. The amino acid is a member of the family of the "fat" amino-acids with high lipophilicity and
Xuejing Yu et al.
The FEBS journal, 281(1), 391-400 (2013-11-12)
Branched-chain amino acid aminotransferase (BCAT) plays a key role in the biosynthesis of hydrophobic amino acids (such as leucine, isoleucine and valine), and its substrate spectrum has not been fully explored or exploited owing to the inescapable restrictions of previous

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