710377

Bis(4-methoxyphenyl)chlorophosphine

85%

• Synonym(s): P,P-Bis(4-methoxyphenyl)phosphinous chloride
• Empirical Formula (Hill Notation): C₁₄H₁₄ClO₂P
• CAS Number: 13685-30-8
• Molecular Weight: 280.69
• MDL number: MFCD04972301
• UNSPSC Code: 12352112
• PubChem Substance ID: 329762919
• NACRES: NA.22

Properties

• assay: 85%
• form: solid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• mp: 62-66 °C
• functional group: phosphine
• SMILES string: COc1ccc(cc1)P(Cl)c2ccc(OC)cc2
• InChI: 1S/C14H14ClO2P/c1-16-11-3-7-13(8-4-11)18(15)14-9-5-12(17-2)6-10-14/h3-10H,1-2H3
• InChI key: YTFQUBRFOJIJOZ-UHFFFAOYSA-N

Description

Application

Reactant for asymmetric:

• Allylic substitution
• Intermolecular Pauson-Khand reaction of symmetrically substituted alkynes
• Hydrogenation
• Intramolecular α-arylation of aldehydes

Reactant for:

• Alcoholysis of phosphane-boranes
• Probing hemilabile sites of Bis(phosphine) monoxide ligands

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges