695815

Bis(4-methylphenyl)chlorophosphine

96%

• Synonym(s): P,P-Bis(4-methylphenyl)-phosphinous chloride, Chlorodi-p-tolylphosphine
• Empirical Formula (Hill Notation): C₁₄H₁₄ClP
• CAS Number: 1019-71-2
• Molecular Weight: 248.69
• MDL number: MFCD01630844
• UNSPSC Code: 12352002
• PubChem Substance ID: 329761777
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 96%
• form: liquid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• refractive index: n20/D 1.501
• density: 1.1 g/mL at 25 °C
• functional group: phosphine
• SMILES string: Cc1ccc(cc1)P(Cl)c2ccc(C)cc2
• InChI: 1S/C14H14ClP/c1-11-3-7-13(8-4-11)16(15)14-9-5-12(2)6-10-14/h3-10H,1-2H3
• InChI key: BJBXRRHIBSXGLF-UHFFFAOYSA-N

Description

Application

Reactant for synthesis of:

• Palladium catalysts for C-C bond forming cross-coupling reactions
• Ligands for nickel(0)-catalyzed isomerization reactions
• Phosphinosulfonamide nickel complexes for oligomerization reactions

Reactant for:

• Pd-catalyzed intramolecular asymmetric allylic amination and ring-closing metathesis
• Phosphinylation reactions

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• supp_hazards: EUH014
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter