686816

5-Bromopyridine-3-boronic acid

≥95%

• Synonym(s): (3-Bromopyridin-5-yl)boronic acid, (5-Bromo-3-pyridyl)boronic acid, (5-bromo-3-pyridinyl)boronic acid
• Empirical Formula (Hill Notation): C₅H₅BBrNO₂
• CAS Number: 452972-09-7
• Molecular Weight: 201.81
• MDL number: MFCD02685634
• UNSPSC Code: 12352103
• PubChem Substance ID: 329761076
• NACRES: NA.22

Properties

• assay: ≥95%
• form: powder
• mp: 260 (dec.)
• storage temp.: 2-8°C
• SMILES string: OB(O)c1cncc(Br)c1
• InChI: 1S/C5H5BBrNO2/c7-5-1-4(6(9)10)2-8-3-5/h1-3,9-10H
• InChI key: ICCGFOKNFZWCTJ-UHFFFAOYSA-N

Description

General description

May contain varying amounts of anhydride.

Application

Reactant for preparation of:

• Thienylpyridyl garlands via cross-coupling with heteroaryl halides
• Arenes via nickel-catalyzed cross-coupling with potassium aryl- and heteroaryl trifluoroborates
• Meso-substituted ABCD-type porphyrins by functionalization reactions
• Analogs of (acetylamino)(dimethylpyrazol)(pyridyl)pyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson′s disease
• 5-hydroxy-1,3,2-dioxaborolan-4-ones boronate-amine complexes via heterocyclization with α-oxocarboxylic acids followed by subsequent complexation
• Radioligands with optimized brain kinetics for PET imaging of nAChR

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves