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685666

Sigma-Aldrich

N,N′-Diisopropylcarbodiimide, ChemDose tablets

Loading: 0.15mmol per tablet

Synonym(s):

N,N′-Diisopropylcarbodiimide impregnated tablets, ChemDose, N,N′-Diisopropylcarbodiimide tablets, DIC impregnated tablets

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About This Item

Linear Formula:
(CH3)2CHN=C=NCH(CH3)2
CAS Number:
Molecular Weight:
126.20
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

form

tablet

matrix

Magnesium aluminometasilicate base material

SMILES string

CC(C)N=C=NC(C)C

InChI

1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3

Inchi Key

BDNKZNFMNDZQMI-UHFFFAOYSA-N

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)

Legal Information

Covered by International Patent Application No. PCT/DK05/000428 and related patent applications, including European Patent Application No. 05753717.7.
ChemDose is a trademark of Reaxa Ltd.

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Huai-Yu Tian et al.
PLoS neglected tropical diseases, 9(3), e0003530-e0003530 (2015-03-31)
Increased risks for hemorrhagic fever with renal syndrome (HFRS) caused by Hantaan virus have been observed since 2005, in Xi'an, China. Despite increased vigilance and preparedness, HFRS outbreaks in 2010, 2011, and 2012 were larger than ever, with a total
K Yamakawa et al.
Journal of thrombosis and haemostasis : JTH, 13(4), 508-519 (2015-01-13)
Although recombinant human soluble thrombomodulin (rhTM) is a widely used novel anticoagulant agent for disseminated intravascular coagulation (DIC) in Japan, its clinical efficacy in sepsis-induced DIC has not been demonstrated convincingly. To assess the benefits and harms of rhTM in
Cody L Gilleland et al.
Genetics, 201(1), 39-46 (2015-07-15)
A major goal in the study of human diseases is to assign functions to genes or genetic variants. The model organism Caenorhabditis elegans provides a powerful tool because homologs of many human genes are identifiable, and large collections of genetic
P J Weber et al.
Bioorganic & medicinal chemistry letters, 8(6), 597-600 (1999-01-01)
A new method has been developed to synthesize fluorescein labeled peptides, compounds of increasing importance in bioorganic chemistry, cell biology, pharmacology, drug targeting and medicinal chemistry. We show, that 4(5)-carboxyfluorescein is much more efficient than the hitherto predominantly utilized reagents
Leila Masri et al.
PLoS biology, 13(6), e1002169-e1002169 (2015-06-05)
Reciprocal coevolution between host and pathogen is widely seen as a major driver of evolution and biological innovation. Yet, to date, the underlying genetic mechanisms and associated trait functions that are unique to rapid coevolutionary change are generally unknown. We

Questions

1–7 of 7 Questions  
  1. Do the ChemDose® tablets disintegrate during the course of the reaction?

    1 answer
    1. They are normally recovered intact, however, they may disintegrate somewhat in aqueous reactions. Any disintegrated tablets can be removed from the reaction via filtration.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  3. What is the pH stability of the ChemDose® tablets?

    1 answer
    1. The ChemDose® tablets are mildly basic and will dissolve in the presence of mineral acids.

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  4. Can I use ChemDose® tablets in a microwave or pressure vessel?

    1 answer
    1. Absolutely. Please see the Technical Information for Download section (below) for additional examples of cross-coupling reactions involving the use of microwaves.

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  5. How should I store ChemDose® tablets?

    1 answer
    1. As with most catalysts and ligands, as a general precaution it is best to store them in a refrigerator and/or under an inert atmosphere to maintain activity. Some catalysts, such as Pd(dppf)Cl2·CH2Cl2, are more robust and can be handled in air without issue. Please refer to the ChemDose® label for specific handling of a given catalyst, ligand, or reagent.

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  6. Can I use ChemDose® tablets in any solvent?

    1 answer
    1. Yes, including aqueous solvents.

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  7. How should I dispose of spent ChemDose® tablets?

    1 answer
    1. They should be treated as solid waste, contaminated with reaction species. The matrix is non-toxic and environmentally benign.

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