They are normally recovered intact, however, they may disintegrate somewhat in aqueous reactions. Any disintegrated tablets can be removed from the reaction via filtration.
685666
N,N′-Diisopropylcarbodiimide, ChemDose™ tablets
Loading: 0.15mmol per tablet
Synonym(s):
N,N′-Diisopropylcarbodiimide impregnated tablets, ChemDose™, N,N′-Diisopropylcarbodiimide tablets, DIC impregnated tablets
About This Item
form
tablet
matrix
Magnesium aluminometasilicate base material
SMILES string
CC(C)N=C=NC(C)C
InChI
1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3
Inchi Key
BDNKZNFMNDZQMI-UHFFFAOYSA-N
Gene Information
human ... EPHX2(2053)
mouse ... Ephx2(13850)
Legal Information
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk_germany
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Do the ChemDose® tablets disintegrate during the course of the reaction?
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What is the pH stability of the ChemDose® tablets?
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The ChemDose® tablets are mildly basic and will dissolve in the presence of mineral acids.
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Can I use ChemDose® tablets in a microwave or pressure vessel?
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Absolutely. Please see the Technical Information for Download section (below) for additional examples of cross-coupling reactions involving the use of microwaves.
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How should I store ChemDose® tablets?
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As with most catalysts and ligands, as a general precaution it is best to store them in a refrigerator and/or under an inert atmosphere to maintain activity. Some catalysts, such as Pd(dppf)Cl2·CH2Cl2, are more robust and can be handled in air without issue. Please refer to the ChemDose® label for specific handling of a given catalyst, ligand, or reagent.
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Can I use ChemDose® tablets in any solvent?
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Yes, including aqueous solvents.
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How should I dispose of spent ChemDose® tablets?
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They should be treated as solid waste, contaminated with reaction species. The matrix is non-toxic and environmentally benign.
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