683965

2,4-Bis(trifluoromethyl)phenylboronic acid

≥95%

• Synonym(s): (2,4-Ditrifluoromethylphenyl)boronic acid, 2,4-Bis(trifluoromethyl)benzeneboronic acid, 2,4-Di(trifluoromethyl)benzeneboronic acid
• Empirical Formula (Hill Notation): C₈H₅BF₆O₂
• CAS Number: 153254-09-2
• Molecular Weight: 257.93
• MDL number: MFCD01631349
• UNSPSC Code: 12352103
• PubChem Substance ID: 24885790
• NACRES: NA.22

Properties

• assay: ≥95%
• form: crystals
• mp: 110-117 °C
• functional group: fluoro
• SMILES string: OB(O)c1ccc(cc1C(F)(F)F)C(F)(F)F
• InChI: 1S/C8H5BF6O2/c10-7(11,12)4-1-2-6(9(16)17)5(3-4)8(13,14)15/h1-3,16-17H
• InChI key: WLYPBMBWKYALCG-UHFFFAOYSA-N

Description

Application

Reactant for preparation of:

• Pyrrolo[2,3-d]pyrimidin-4-ones as corticotropin-releasing factor 1 receptor antagonists with a carbonyl-based hydrogen bonding acceptor
• Biaryl pyrazole carboxamides as sodium channel blockers for treatment of neuropathic pain
• Biphenylketones as dual modulators of inflammation and bone loss
• (Biphenylyl)pyrazolecarboxamides and their voltage-gated sodium channel Nav1.7 blocking structure-activity relationship
• N-hydroxyalkyl biphenylsulfonamides as inhibitors of bone resorption
• 1,3,6,8a-tetraazaacenaphthylene derivatives and study of their activity as corticotropin-releasing factor-1 antagonists
• Blue luminescent iridium phenylpyridine complexes

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable