683876

4-Aminocarbonylphenylboronic acid

≥95%

• Synonym(s): 4-Carbamoylbenzeneboronic acid, 4-Carbamoylphenylboronic acid
• Linear Formula: (H₂NCO)C₆H₄B(OH)₂
• CAS Number: 123088-59-5
• Molecular Weight: 164.95
• MDL number: MFCD03411940
• UNSPSC Code: 12352103
• PubChem Substance ID: 24885784
• NACRES: NA.22

Properties

• assay: ≥95%
• form: powder or crystals
• mp: 229-234 °C
• functional group: amide
• storage temp.: 2-8°C
• SMILES string: NC(=O)c1ccc(cc1)B(O)O
• InChI: 1S/C7H8BNO3/c9-7(10)5-1-3-6(4-2-5)8(11)12/h1-4,11-12H,(H2,9,10)
• InChI key: GNRHNKBJNUVWFZ-UHFFFAOYSA-N

Description

Application

Reactant involved in:

• Suzuki-Miyaura, Sonogashira and Buchwald-Hartwig cross-coupling reactions for the synthesis of substituted pyrene derivatives
• Suzuki-Miyaura reactions for the synthesis of aryl-substituted oxabenzindoles and methanobenzindoles or 2-aminoimidazole triazoles
• Three-component coupling with triflates and alkenes

Reactant involved in synthesis of biologically active molecules including:

• Hybrid peptidomimetic molecules as STAT3 protein inhibitors
• Vasopressin V1B receptor antagonists for use as antidepressants oand anxiolytics
• (Thienopyridine)caboxamides as CHK1 inhibitors

Safety Information

• Pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 + P330 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves