680524

2-Chloro-5-(trifluoromethyl)phenylboronic acid

• Synonym(s): 2-Chloro-5-(trifluoromethyl)benzeneboronic acid
• Empirical Formula (Hill Notation): C₇H₅BClF₃O₂
• CAS Number: 182344-18-9
• Molecular Weight: 224.37
• MDL number: MFCD00797335
• UNSPSC Code: 12352103
• PubChem Substance ID: 329760735

Properties

• SMILES string: OB(O)c1cc(ccc1Cl)C(F)(F)F
• InChI: 1S/C7H5BClF3O2/c9-6-2-1-4(7(10,11)12)3-5(6)8(13)14/h1-3,13-14H
• InChI key: YVMXEHZEYONARR-UHFFFAOYSA-N

Description

Application

Reactant for:

• Synthesis of aryl- and hetarylfurocoumarins via Suzuki reaction
• Synthesis of Et canthinone-3-carboxylates from Et 4-bromo-6-methoxy-1,5-naphthyridine-3-carboxylate via a Pd-catalyzed Suzuki-Miyaura coupling and a Cu-catalyzed amidation reaction
• Preparation of xanthines via one-pot coupling with diaminouracil
• Pd-catalyzed Suzuki-Miyaura coupling with 8-bromo-1,5-naphthyridin-2-one

May contain varying amounts of anhydride.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves