680214

N-Boc-4-piperidineacetaldehyde

97%

• Synonym(s): 4-(2-Oxoethyl)piperidine-1-carboxylic acid, tert-butyl ester, tert-Butyl 4-(formylmethyl)piperidine-1-carboxylate
• Empirical Formula (Hill Notation): C₁₂H₂₁NO₃
• CAS Number: 142374-19-4
• Molecular Weight: 227.30
• MDL number: MFCD03425258
• UNSPSC Code: 12352100
• PubChem Substance ID: 24885547
• NACRES: NA.22

Properties

• assay: 97%
• form: solid
• mp: 38-42 °C
• application(s): peptide synthesis
• functional group: aldehyde
• SMILES string: [H]C(=O)CC1CCN(CC1)C(=O)OC(C)(C)C
• InChI: 1S/C12H21NO3/c1-12(2,3)16-11(15)13-7-4-10(5-8-13)6-9-14/h9-10H,4-8H2,1-3H3
• InChI key: PSRHRFNKESVOEL-UHFFFAOYSA-N

Description

Application

Reactant for synthesis of:

• Pim-1 inhibitors
• Selective GPR119 agonists for type II diabetes

Reactant for:

• α-arylation of aldehydes
• Enantioselective α-benzylation of aldehydes via photoredox organocatalysis
• Enantioselective α−triflouromethylation of aldehydes

Building block employed in a synthesis of (S)-quinuclidine-2-carboxylic acid. Substrate used in an enanioselective organo-catalytic α-vinylation reaction.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: >230.0 °F
• flash_point_c: > 110 °C
• ppe: dust mask type N95 (US), Eyeshields, Gloves