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Key Documents

672742

Sigma-Aldrich

5-Hydroxynicotinic acid

97%

Synonym(s):

5-Hydroxypyridine-3-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C6H5NO3
CAS Number:
Molecular Weight:
139.11
Beilstein/REAXYS Number:
115847
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

≥96.5% (HPLC)
97%

SMILES string

Oc1cncc(c1)C(O)=O

InChI

1S/C6H5NO3/c8-5-1-4(6(9)10)2-7-3-5/h1-3,8H,(H,9,10)

InChI key

ATTDCVLRGFEHEO-UHFFFAOYSA-N

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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P Chaiyen et al.
Biochemistry, 36(26), 8060-8070 (1997-07-01)
The oxygenation reaction of 2-methyl-3-hydroxypyridine-5-carboxylic acid (MHPC) oxygenase with the substrate, MHPC, was investigated. Two oxygenated flavin intermediates C(4a)-hydroperoxy flavin and C(4a)-hydroxy flavin were found, implying that the enzyme functions similarly to flavoprotein hydroxylases. This finding is supported by the
Yi Li et al.
Cell chemical biology, 27(7), 858-865 (2020-05-30)
The engineered ascorbate peroxidase (APEX) is a powerful tool for the proximity-dependent labeling of proteins and RNAs in live cells. Although widely use in mammalian cells, APEX applications in microorganisms have been hampered by the poor labeling efficiency of its

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