660078

(R)-(−)-1-Cbz-3-aminopyrrolidine

97%

• Synonym(s): (R)-1-Benzyloxycarbonyl-3-aminopyrrolidine
• Empirical Formula (Hill Notation): C₁₂H₁₆N₂O₂
• CAS Number: 122536-73-6
• Molecular Weight: 220.27
• MDL number: MFCD05864624
• UNSPSC Code: 12352005
• PubChem Substance ID: 24884456
• NACRES: NA.22

Properties

• assay: 97%
• refractive index: n20/D 1.548
• bp: 315 °C
• density: 1.155 g/mL at 25 °C
• functional group: phenyl
• SMILES string: N[C@@H]1CCN(C1)C(=O)OCc2ccccc2
• InChI: 1S/C12H16N2O2/c13-11-6-7-14(8-11)12(15)16-9-10-4-2-1-3-5-10/h1-5,11H,6-9,13H2/t11-/m1/s1
• InChI key: FPXJNSKAXZNWMQ-LLVKDONJSA-N

Description

Application

(R)-(−)-1-Cbz-3-aminopyrrolidine can be used:

• In one of the key synthetic steps for the preparations of AZ82, a KIFC1-specific inhibitor for cancer therapy.
• As a key intermediate in the synthesis of N⁶-substituted adenosine analogs as potent A₁AR agonists.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: >230.0 °F - closed cup
• flash_point_c: > 110 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter