654299

(R)-(+)-o-Tolyl-CBS-oxazaborolidine solution

0.5 M in toluene

• Synonym(s): (R)-(+)-3,3-Diphenyl-1-o-tolyl-tetrahydropyrrolo(1,2-c)(1,3,2)oxazaborole
• Empirical Formula (Hill Notation): C₂₄H₂₄BNO
• CAS Number: 865812-10-8
• Molecular Weight: 353.26
• MDL number: MFCD07369781
• UNSPSC Code: 12352005
• PubChem Substance ID: 24884025
• NACRES: NA.22

Properties

• concentration: 0.5 M in toluene
• refractive index: n20/D 1.514
• density: 0.900 g/mL at 25 °C
• functional group: phenyl
• SMILES string: [H][C@]12CCCN1B(OC2(c3ccccc3)c4ccccc4)c5ccccc5C
• InChI: 1S/C24H24BNO/c1-19-11-8-9-16-22(19)25-26-18-10-17-23(26)24(27-25,20-12-4-2-5-13-20)21-14-6-3-7-15-21/h2-9,11-16,23H,10,17-18H2,1H3/t23-/m1/s1
• InChI key: XHMKFCAQQGBIPZ-HSZRJFAPSA-N

Description

Application

CBS Catalysts for Asymmetric Reduction and Asymmetric Synthesis

When protonated with trifluoromethanesulfonimide, chiral oxazaborolidines generate chiral Lewis acids, which have demonstrated great utility in the enantioselective Diels-Alder reaction.

Safety Information

• pictograms: GHS02,GHS08,GHS07
• signalword: Danger
• hcodes: H225,H304,H315,H336,H361d,H373,H412
• pcodes: P201 - P210 - P273 - P301 + P310 + P331 - P302 + P352 - P308 + P313
• Hazard Classifications: Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 39.2 °F - closed cup
• flash_point_c: 4 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter