Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

60034

Sigma-Aldrich

4-Aminophenol

≥99% (HPLC)

Synonym(s):

4-Hydroxyaniline

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
H2NC6H4OH
CAS Number:
123-30-8
Molecular Weight:
109.13
Beilstein/REAXYS Number:
385836
EC Number:
204-616-2
MDL number:
MFCD00007869
UNSPSC Code:
12352100
PubChem Substance ID:
57651713

assay

≥99% (HPLC)

form

powder

mp

185-189 °C (lit.)
186-188 °C

solubility

water: slightly soluble

SMILES string

Nc1ccc(O)cc1

InChI

1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2

InChI key

PLIKAWJENQZMHA-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

4-Aminophenol is an organic building block. Its voltammetric estimation in water samples by employing single-wall carbon nanotubes (SWNT)-Nafion film coated glassy carbon electrode has been reported. It is present as the main contaminant in the pharmaceutical formulation of paracetamol. Its quantification in multicomponent dosage preparations of paracetamol by HPLC coupled with amperometric detection has been described.

Application

4-Aminophenol may be used in the synthesis of 2,2-bis(4-aminophenoxy) benzonitrile [4-APBN], a monomer required for the preparation of series of polyamides and poly(amide-imide)s. It may be used as derivatization reagent during paper spray ionization mass spectrometric estimation of aldehydes.

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2

target_organs

Kidney

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SZBG2300V
STBG4700V
SZBF3090V
SZBF3090
SZBF0140V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis and characterization of polyamides and poly (amide-imide) s derived from 2, 2-bis (4-aminophenoxy) benzonitrile.
Saxena A, et al.
European Polymer Journal, 39(2), 401-405 (2003)
Pravin B Patil et al.
Ultrasonics sonochemistry, 70, 105306-105306 (2020-08-17)
The present study reports significant improvements in the removal of ammoniacal nitrogen from wastewater which is an important problem for many industries such as dyes and pigment, distilleries and fisheries. Pilot plant studies (capacity, 1 m3/h) on synthetic wastewater using 4-amino
E Wyszecka-Kaszuba et al.
Journal of pharmaceutical and biomedical analysis, 32(4-5), 1081-1086 (2003-08-06)
A method for the determination of 4-aminophenol, the main impurity of paracetamol, by high-performance liquid chromatographic (HPLC) method with amperometric detection has been developed. The analysis was performed in an isocratic mode on a reversed phase Luna column 5 microm
Wensheng Huang et al.
Talanta, 61(3), 411-416 (2008-10-31)
A single-wall carbon nanotubes (SWNT)-Nafion film coated glassy carbon electrode (GCE) was described for the determination of 4-aminophenol. In pH 3.0 sodium citrate-HCl buffer, the oxidation peak current of 4-aminophenol increases greatly at the SWNT-Nafion film coated GCE in contrast
Y Xu et al.
Clinical chemistry, 36(11), 1941-1944 (1990-11-01)
A sandwich-type heterogeneous enzyme immunoassay with flow-injection analysis for alpha-fetoprotein (AFP) in human serum has been developed. 4-Aminophenol, the product of enzymatic reaction, is detected amperometrically. The interassay CV for this electrochemical enzyme immunoassay was less than 8.2%, with a
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service