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Key Documents

564613

Sigma-Aldrich

5-Amino-2-nitrobenzoic acid

97%

Synonym(s):

2-Nitro-5-aminobenzoic acid, 3-Carboxy-4-nitroaniline, NSC 74455

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About This Item

Linear Formula:
H2NC6H3(NO2)CO2H
CAS Number:
Molecular Weight:
182.13
Beilstein/REAXYS Number:
2107512
EC Number:
MDL number:
UNSPSC Code:
12352106
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

97%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

236-238 °C (lit.)

application(s)

peptide synthesis

SMILES string

Nc1ccc(c(c1)C(O)=O)[N+]([O-])=O

InChI

1S/C7H6N2O4/c8-4-1-2-6(9(12)13)5(3-4)7(10)11/h1-3H,8H2,(H,10,11)

InChI key

KZZWQCKYLNIOBT-UHFFFAOYSA-N

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Application

Reactant for:
  • Two-component dendritic chain reactions
  • Enzymic activation of hydrophobic self-immolative dendrimers
  • Preparation of insulin receptor tyrosine kinase activator
  • Preparation of polymer-bound diazonium salts using Merrifield resin-bound piperazine

pictograms

Flame over circle

signalword

Danger

hcodes

Hazard Classifications

Ox. Sol. 2

Storage Class

5.1B - Oxidizing hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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F Schiele et al.
Clinical chemistry, 33(11), 1978-1982 (1987-11-01)
We describe the process of certification for a gamma-glutamyltransferase reference material (CRM no. 319). Fifteen laboratories participated to this interlaboratory evaluation. All steps of the measurements were controlled in an effort to locate potential sources of variations. In particular, the
Eran Sella et al.
Chemical communications (Cambridge, England), 46(35), 6575-6577 (2010-08-18)
A new dendritic chain reaction probe system was demonstrated to produce exponential signal amplification for the detection of sulfhydryl compounds.
A Balamurugan et al.
Biosensors & bioelectronics, 24(4), 982-986 (2008-09-09)
Herein, we reported for the first time one step procedure for the preparation of cytochrome c (cyt c)-poly (5-amino-2-napthalenesulfonic acid) (PANS) modified glassy carbon electrode by cyclic voltammetrically (CV). Hereafter, we called the above modified electrode as cyt c-PANS electrode.
5-amino-2-nitrobenzoic acid as a reference material for the determination of gamma-GT activity.
S Yamadate et al.
Clinica chimica acta; international journal of clinical chemistry, 160(1), 63-67 (1986-10-15)
Valeria Calcaterra et al.
Frontiers in pediatrics, 8, 591012-591012 (2020-12-18)
Background: Chronic low-grade inflammation and activation of the immune system are hallmark pathogenic mechanisms involved in metabolic dysfunction and are related to obesity. In particular, the involvement of regulatory and pro-inflammatory lymphocyte subpopulations has been reported in adults. We evaluated

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