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Key Documents

55709

Sigma-Aldrich

3-(4-Hydroxymethylphenoxy)propionic acid

≥98.0% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C10H12O4
CAS Number:
Molecular Weight:
196.20
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

≥98.0% (HPLC)

reaction suitability

reagent type: cross-linking reagent

mp

148-152 °C

SMILES string

OCc1ccc(OCCC(O)=O)cc1

InChI

1S/C10H12O4/c11-7-8-1-3-9(4-2-8)14-6-5-10(12)13/h1-4,11H,5-7H2,(H,12,13)

InChI key

WPWKJUVXEMKOHS-UHFFFAOYSA-N

Other Notes

Handle used in solid phase peptide synthesis[1]

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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F Albericio et al.
International journal of peptide and protein research, 26(1), 92-97 (1985-07-01)
Several Fmoc-amino acids have been esterified by use of N,N-dimethylformamide dineopentyl acetal to 2,4,5-trichlorophenyl 3'-(4''-hydroxymethyl-phenoxy)propionate, and the resultant handle derivatives were purified and then quantitatively coupled onto aminomethyl supports. Compared to literature methodology, the present procedure is preferred because: (i)

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