543136

Propargyl acrylate

98%

• Synonym(s): Acrylic acid propargyl ester
• Linear Formula: CH₂=CHCO₂CH₂C≡CH
• CAS Number: 10477-47-1
• Molecular Weight: 110.11
• EC Number: 233-975-8
• MDL number: MFCD00078451
• UNSPSC Code: 12352100
• PubChem Substance ID: 24878664
• NACRES: NA.22

Properties

• assay: 98%
• contains: 200 ppm BHT as inhibitor
• refractive index: n20/D 1.447 (lit.)
• bp: 142-143 °C (lit.)
• density: 0.997 g/mL at 25 °C (lit.)
• functional group: acrylate; ester
• SMILES string: C=CC(=O)OCC#C
• InChI: 1S/C6H6O2/c1-3-5-8-6(7)4-2/h1,4H,2,5H2
• Inchi Key: WPBNLDNIZUGLJL-UHFFFAOYSA-N

Description

General description

Propargyl acrylate is a propargyl ester of acrylic acid. It participates in the preparation of lipid nanoparticles for use in siRNA delivery.

Application

Propargyl acrylate may be used to synthesize:

• linear poly(N-isopropylacrylamide)(PNIPAM)
• 1-[3-(2-methyl-2-dodecylsulfanylthiocarbonylsulfanylpropionyloxy)propyl]-1H-[1,2,3]triazol-4-ylmethyl acrylate, an acryloyl trithiocarbonate chain transfer agent
• propranolol-imprinted core–shell nanoparticles (mipCS)

Safety Information

• pictograms: GHS02,GHS07
• signalword: Warning
• hcodes: H226,H315,H319,H335
• pcodes: P210 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 109.9 °F - closed cup
• flash_point_c: 43.3 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter